Results 151 to 160 of about 755,044 (345)

The use of topical diclofenac in the pain management of osteoarthritis of the knee [PDF]

, 2006
Osteoarthritis (OA) is a common complaint that affects millions of people worldwide. As there is no cure for OA, drug treatment is the main form of management.
Banning, M
core  

Integrative single cell RNA‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objectives Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell‐cell interactions in FAI and hip OA.
Gulzada Kulzhanova, Alexis Klee, Mina Botros, Victoria L. Hansen, John Reuter, Eliya Tazreena Tashbib, Eloise Fadial, Benjamin F. Ricciardi, Brian Giordano, Chia‐Lung Wu   +9 more
wiley   +1 more source

Machine learning and deep neural network-based learning in osteoarthritis knee. [PDF]

World J Methodol, 2023
Ratna HVK, Jeyaraman M, Jeyaraman N, Nallakumarasamy A, Sharma S, Khanna M, Gupta A.   +6 more
europepmc   +1 more source

The International Workshop on Osteoarthritis Imaging Knee MRI Segmentation Challenge: A Multi-Institute Evaluation and Analysis Framework on a Standardized Dataset

, 2020
Purpose: To organize a knee MRI segmentation challenge for characterizing the semantic and clinical efficacy of automatic segmentation methods relevant for monitoring osteoarthritis progression.
Akcakaya, Mehmet, Bagci, Ulas, Caliva, Francesco, Chaudhari, Akshay S., Dam, Erik B., Deniz, Cem M., Desai, Arjun D., Ellermann, Jutta, Flament, Io, Gaj, Sibaji, Gold, Garry E., Hargreaves, Brian A., Igel, Christian, Iriondo, Claudia, Jambawalikar, Sachin, Juras, Vladimir, Khosravan, Naji, Li, Xiaojuan, Majumdar, Sharmila, Mortazi, Aliasghar, Nakamura, Kunio, O`Brien, Matthew, Pai, Akshay, Pedoia, Valentina, Perslev, Mathias, Regatte, Ravinder, Tibrewala, Radhika, Torigian, Drew, Yang, Mingrui   +28 more
core  

Visual Hypersensitivity as a Transdiagnostic Marker of Surgical Pain Response in Arthritis and Chronic Pain Syndromes

Arthritis &Rheumatology, EarlyView.
Objective Nociplastic pain is pain primarily driven by the central nervous system and, unlike nociceptive pain conditions, is thought to be refractory to peripherally directed therapies. Nociplastic pain is also associated with hypersensitivity to painful and other sensory stimuli (such as visual stimuli). Nonpainful sensory measures have not been well
Noah Waller, Steven E. Harte, Richard E. Harris, Andrew Schrepf, Tristin Smith, Eric Ichesco, Chelsea Kaplan, Flavia Sunzini, Deeba Minhas, Wendy Marder, Sara R. Till, David A. Williams, Chad M. Brummett, Neil Basu, Sawsan As‐Sanie, Daniel J. Clauw   +15 more
wiley   +1 more source

Quantitative ultrasound assessment of gastrocnemius muscle changes in patients with knee osteoarthritis

Journal of International Medical Research
Background Knee osteoarthritis presents with posterior knee pain, stiffness, and restricted mobility, potentially affecting periarticular muscle biomechanics.
Hui Zuo, Ting Xu, Qianwen Wang, Wei Tan, Xu Liu   +4 more
doaj   +1 more source

Osteoarthritis knee and modifiable cardiovascular risk factors: play in tandem. [PDF]

Pak J Med Sci, 2023
Wagan AA, Surahyo P, Bhutto AQ, Asghar A.   +3 more
europepmc   +1 more source

Cellular characterisation of advanced osteoarthritis knee synovium. [PDF]

Arthritis Res Ther, 2023
Mimpen JY, Hedley R, Ridley A, Baldwin MJ, Windell D, Bhalla A, Ramos-Mucci L, Buckley CD, Coles MC, Alvand A, Price AJ, Carr AJ, Dakin SG, Snelling SJB.   +13 more
europepmc   +1 more source

Tissue‐Specific and Spatially Dependent Metabolic Signatures Perturbed by Injury in Male and Female Mice

Arthritis &Rheumatology, EarlyView.
Objective Osteoarthritis, the leading cause of disability worldwide, disproportionately affects women, yet sex remains an overlooked determinant. This disparity stems from sex‐specific differences in injury susceptibility—a major risk factor for disease.
Hope D. Welhaven, Avery H. Welfley, Priyanka P. Brahmachary, Mark Greenwood, Donald F. Smith, Brian Bothner, Ronald K. June   +6 more
wiley   +1 more source

CD14 Plays a Critical Role in Pain and Inflammation Across Multiple Models of Post‐traumatic Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective We employed global genetic deletion of CD14 and intra‐articular CD14 blockade across multiple murine osteoarthritis (OA) models that vary in severity of pathology and rate of progression to test the hypothesis that CD14 inhibition attenuates synovial inflammation and associated pain during disease progression.
Kevin G. Burt, Sanique M. South, Natalie S. Adamczyk, Vu Nguyen, Shingo Ishihara, Cheng Zhou, Kate L. Sharp, Sung Y. Kim, Anna E. Rapp, Baofeng Hu, Lance A. Murphy, Li‐Yin Hung, De'Broski Herbert, Joshua F. Baker, Robert L. Mauck, Timothy M. Griffin, Anne‐Marie Malfait, Rachel E. Miller, Carla R. Scanzello   +18 more
wiley   +1 more source