Results 191 to 200 of about 708,008 (375)

Integrin αVβ3 Signaling in the Progression of Osteoarthritis Induced by Excessive Mechanical Stress [PDF]

, 2022
Fanglong Song, Xiaoyu Mao, Jun Dai, Bingchen Shan, Zhentao Zhou, Yifan Kang   +5 more
openalex   +1 more source

Near‐Infrared Switch‐Driven Macrophage Dynamically Reprogramming for Anti‐Infection and Tissue Healing on Polyetheretherketone Implants

Advanced Science, EarlyView.
This study develops a Mg‐H‐SPEEK implant with NIR‐switchable immunomodulatory properties. Under NIR, it promotes M1 macrophages for antibacterial action; without NIR, it induces M2 reprogramming to enhance tissue healing. This dual‐function material offers a smart strategy for reducing infection and improving integration in percutaneous implants ...
Yinghao Wu, Shuaiqi Jiang, Jibing He, Ji Tan, Junjie Zhou, Zhipeng Zou, Jiaxing Wang, Jia Jiang, Xuanyong Liu, Xiaochun Peng   +9 more
wiley   +1 more source

Multidisciplinary consensus on the management of patients with osteopenia and fracture risk in Spain

BMC Musculoskeletal Disorders
Background In Spain, over 3.5 million individuals are diagnosed with osteoporosis, while an even greater number are affected by osteopenia, the precursor stage of this severe condition.
Jose Luis Baquero Úbeda, Silvia García Díaz, Jesús-Carlos Gómez Martínez, Nina Martínez Fernández, Rafael Manuel Micó Pérez, Ingrid Möller, José Luis Neyro Bilbao, Pilar Saez López, Manuel Santiñà Vila, Josep Vergés Milano, Task Force Members   +10 more
doaj   +1 more source

Longitudinal Relationship Between Physical Activity and Joint Space Narrowing: Forty‐Eight–Month Follow‐Up Data From the Osteoarthritis Initiative [PDF]

, 2021
Bo Hu, DongBai Han, Michael C. Nevitt, Burton L. Wise, Neil A. Segal   +4 more
openalex   +1 more source

Mechanisms and therapeutic implications of cellular senescence in osteoarthritis

Nature Reviews Rheumatology, 2020
Philip Coryell, B. Diekman, R. Loeser
semanticscholar   +1 more source

Mechanical Stress Triggers Premature Senescence in Cardiac Fibroblasts

Advanced Science, EarlyView.
Cellular senescence contributes to disease burden in cardiovascular disease (CVD) and aging, highlighting the need to understand its induction. In primary cardiac fibroblasts, reduced strain and increased frequency, mimicking CVD, elicit a distinct senescent phenotype compared to oxidative stress.
Stephanie E. Schneider, Adrienne K. Scott, Katie M. Gallagher, Emily Y. Miller, Soham Ghosh, Corey P. Neu   +5 more
wiley   +1 more source

Osteoarthritis: musculoskeletal fact sheet [PDF]

This fact sheet summarises information from the AIHW\u27s online musculoskeletal compendium. Summary Osteoarthritis is a degenerative condition mostly affecting the joints such as hips, knees and ankles.
Australian Institute of Health and Welfare
core  

LncRNA TM1‐3P Regulates Proliferation, Apoptosis and Inflammation of Fibroblasts in Osteoarthritis through miR‐144‐3p/ONECUT2 Axis [PDF]

, 2022
Yangfei Yi, Ningyin Yang, Zirui Yang, Xiaojun Tao, Yufei Li   +4 more
openalex   +1 more source

Organic Electrochemical Transistors in Tissue‐Interfaced Bioelectronics

Advanced Science, EarlyView.
This article reviews the design, fabrication, and biological application of organic electrochemical transistors (OECTs), emphasizing their potential in tissue‐interfaced bioelectronics. It covers the fundamental principles of OECTs, strategies for enhancing tissue interfacing, and the development of skin‐mounted and implantable systems.
Ruixiang Bai, Zeyu Zhao, Feng Yan
wiley   +1 more source

Identification and Mechanisms of Osteocyte Subsets Involved in the Pathological Progression of Osteoporosis

Advanced Science, EarlyView.
Osteocyte heterogeneity in bone remains poorly understood. This study identifies six distinct osteocyte subsets in mice, revealing a key subpopulation (BHR‐Ocys) that drives bone loss in osteoporosis. BHR‐Ocys promote osteoclast‐mediated resorption via a novel Sema5a‐Plxna1 signaling axis.
Zengxin Jiang, Biyu Rui, Xuecheng He, Jiajun Wang, Xiangdong Wu, Rui Shao, Xue Meng, Xiaochun Peng, Hengfeng Yuan   +8 more
wiley   +1 more source