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Osteoarthritis

Inflammopharmacology, 2023
The clinical appearance and radiological pattern of osteoarthritis have been identified in the skeletons of dinosaurs some 50-70 million years old, and in Egyptian mummies, and in ancient skeletons in England. Osteoarthritis patterns of joint involvement, often referred to as primary osteoarthritis, can be seen in the hands, spinal facet joints, hips ...
W Watson, Buchanan   +3 more
openaire   +4 more sources

Osteoarthritis

The Lancet, 2015
Osteoarthritis is a major source of pain, disability, and socioeconomic cost worldwide. The epidemiology of the disorder is complex and multifactorial, with genetic, biological, and biomechanical components. Aetiological factors are also joint specific.
Glyn-Jones, S   +6 more
openaire   +7 more sources

Osteoarthritis

The Lancet, 2019
Osteoarthritis is a leading cause of disability and source of societal cost in older adults. With an ageing and increasingly obese population, this syndrome is becoming even more prevalent than in previous decades. In recent years, we have gained important insights into the cause and pathogenesis of pain in osteoarthritis.
Hunter, DJ, Bierma - Zeinstra, Sita
openaire   +2 more sources

Osteoarthritis

Science of Aging Knowledge Environment, 2004
In this case study, we describe the symptoms, evaluation, and management of a woman with osteoarthritis (OA). OA is the most common form of arthritis worldwide and it is a major cause of disability in the elderly. Although there are several aging-related changes in the musculoskeletal system that may contribute to the pathogenesis of this disease ...
Najia, Shakoor, Richard F, Loeser
openaire   +4 more sources

Osteoarthritis

Best Practice & Research Clinical Rheumatology, 2008
Osteoarthritis (OA) is a chronic degenerative disorder characterized by cartilage loss. Its prevalence is high, and it is a major cause of disability. The cause of OA is not known; however, current evidence indicates that it is multifactorial. Major risk factors for osteoarthritis are age, female sex, obesity, geographic factors, occupational knee ...
Siddharth Kumar, Das, Abid, Farooqi
openaire   +2 more sources

Osteoarthritis

Rheumatic Disease Clinics of North America, 2011
The pathogenesis of osteoarthritis (OA) appears to be the result of a complex interplay between mechanical, cellular and biochemical forces. Obesity is the strongest risk factor for disease onset in the knee, and mechanical factors dominate the risk for disease progression. OA is a highly prevalent and disabling disease.
openaire   +2 more sources

Osteoarthritis

Best Practice & Research Clinical Rheumatology, 1995
There are few studies on the prevalence, pattern or clinical course of osteoarthritis (OA) in the tropics. The studies that have been carried out, however, indicate that on the whole there is a lower prevalence of OA than found in Western countries. In addition, the pattern of joint involvement may be different with less common involvement of the hip ...
openaire   +2 more sources

Osteoarthritis in the hand

The Journal of Hand Surgery, 1983
Patients who have disabling osteoarthritis of the hand are frequently given the wrong diagnosis, poor professional advice and inadequate treatment programmes. The exact cause of primary osteoarthritis remains unknown; however, an interplay of genetic factors, mechanical factors and biomechanical alterations in cartilage seems to be important.
Geneviève de Groot Swanson   +1 more
openaire   +5 more sources

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