Results 51 to 60 of about 4,323,847 (152)

Exome Sequencing Identifies SLCO2A1 Mutations as a Cause of Primary Hypertrophic Osteoarthropathy [PDF]

, 2012
By using whole-exome sequencing, we identified a homozygous guanine-to-adenine transition at the invariant −1 position of the acceptor site of intron 1 (c.97−1G>A) in solute carrier organic anion transporter family member 2A1 (SLCO2A1), which encodes a ...
Yue, Hua, Hu, Weiwei, Hu, Yunqiu, Liu, Yujuan, Wang, Chun, Zhang, Hao, Xia, Weibo, Zhang, Zhenlin, Ke, Yaohua, Gu, Jiemei, Zhang, Zeng, Fu, Wenzhen, He, Jinwei, Li, Miao   +13 more
core   +1 more source

Hypertrophic Osteopathy Associated With Intrathoracic Masses in 5 Dogs and Review of the Literature

Veterinary Medicine International, Volume 2026, Issue 1, 2026.
This study describes the clinical and radiographical findings of hypertrophic osteopathy in 5 female mature adult dogs with pulmonary and mediastinal masses. Besides, the literature review from the past to today provides information about the disease.
Mehmet Alper Cetinkaya, Soner Cagatay, Mehmet Pilli, Ali Curukoglu, Deniz Seyrek Intas, Lipi Buch   +5 more
wiley   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

Australian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt, K Thomas, S Page, J Norris, G Browning, C El Hage, A Stewart, J Gilkerson, G Muscatello, D Verwilghen, G van Galen, J Bauquier, R Cuming, B Reynolds, C Whittaker, E Wilkes, J Clulow, C Burden, L Begg   +18 more
wiley   +1 more source

Touraine–Solente–Gole syndrome: Clinical manifestation with bilateral true eyelid ptosis

JPRAS Open, 2019
Touraine–Solente–Gole syndrome (pachydermoperiostosis [PDP] or primary idiopathic hypertrophic osteoarthropathy [HOA]) is a rare hereditary disorder that is characterized by a triad of manifestations that consists of skin changes (pachydermia), abnormal ...
Nutthawut Akaranuchat, Papassorn Limsuvan   +1 more
doaj   +1 more source

Touraine-Solente-Gole Syndrome: A Rare Case Report

Delhi Journal of Ophthalmology, 2017
Touraine-Solente-Gole Syndrome, also known as Pachydermoperiostosis (PDP) or Primary Hypertrophic Osteoarthropathy, is a rare hereditary disorder, which affects both bones and skin.
Dharmil Doshi, Dipali Satani, Shwetambari Singh   +2 more
doaj   +1 more source

Solitary Fibrous Tumor of the Pleura Presenting as a Giant Thoracic Mass: A Case Report

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Solitary fibrous tumors of the pleura are rare and may present as large thoracic masses. Timely imaging and histopathological confirmation are essential for accurate diagnosis and effective surgical management.
Zahra Sadin, Manouchehr Aghajanzadeh, Mohammadreza Sadin, Arsalan Dadashi, Omid Mosaffaee Rad, Seyed Ali Fakhr Mosavi, Ali Alavi Foumani, Azita Tangestani Nejad, Mohaya Farzin   +8 more
wiley   +1 more source

Cranio-osteoarthropathy in sibs

, 2007
Primary hypertrophic osteoarthropathy is a condition characterized by clubbing, arthropathy and periostosis of long tubular bones. Three variants of primary hypertrophic osteoarthropathy are distinguished: pachydermoperiostosis, which shows as additional
Hennekam, Raoul C. M., Hall, Christine M., Wilson, Louise C., Dabir, Tabib, Sills, A. M., Bennett, Chris   +5 more
core   +1 more source

Primary Hypertrophic Osteoarthropathy (Pachydermoperiostosis): Two Brothers Misdiagnosed As Inflammatory Arthritis

Trends in Urology &Men's Health, Volume 16, Issue 4, August 2025.
ABSTRACT Primary hypertrophic osteoarthropathy (Pachydermoperiostosis) is a rare, inherited genetic disorder of the skeleton and the skin, characterised by clubbing of the fingers, thickening of the skin especially of the face and forehead (pachydermia) and periostosis. Patients often present with pain and swelling of the knees and ankles.
Ahmed AbdulBari, Farooq Fouad, Sarah Mushtaq, Ali Jawad   +3 more
wiley   +1 more source

A Case Study of a Female Infant With Primary Hypertrophic Osteoarthropathy Demonstrates That Early Initiation of Celecoxib Slows but Does Not Prevent Symptom Progression

American Journal of Medical Genetics Part A, Volume 197, Issue 5, May 2025.
ABSTRACT Primary Hypertrophic Osteoarthropathy (PHOAR1) is characterized by autosomal recessive loss of function variants in 15‐hydroxyprostaglandin dehydrogenase (HPGD) leading to digital clubbing, periostosis, pachydermia, and severe hyperhidrosis. HPGD catalyzes the first step of prostaglandin E2 (PGE2) degradation.
Kara Zehr, Morgan Buckley, Joshua W. Owens, Tomas Vanagunas, Patricia Vega Fernandez, Robert J. Hopkin, Amelle Shillington   +6 more
wiley   +1 more source

Hypertrophic osteoarthropathy as a paraneoplastic manifestation of lung cancer. [PDF]

, 2020
Hypertrophic osteoarthropathy (HOA) is a syndrome that consists of periostitis, digital clubbing, and painfulpolyarthropathy. The management and prognosis of HOA is dependent on the underlying disease process.Recognising and treating it accordingly will ...
Rutkowski, Marcin; Oddział Kliniczny Pulmonologii, Alergologii, Chorób Wewnętrznych Szpitala Uniwersyteckiego w Krak owie, Poland, Picco Brunetto, Alba Gabriela; Hospital San Juan de Dios, Calle Beloso Alto 3, 31006 Pamplona, Spain, Masłowska, Aleksandra; Oddział Kliniczny Pulmonologii, Alergologii, Chorób Wewnętrznych Szpitala Uniwersyteckiego w Krak owie, Poland   +2 more
core   +1 more source