Results 1 to 10 of about 4,325,288 (187)

Etoricoxib as a treatment of choice for patients with SLCO2A1 mutation exhibiting autosomal recessive primary hypertrophic osteoarthropathy: A case report [PDF]

Frontiers in Genetics, 2022
We reported a 22-year-old Emirati male with autosomal recessive primary hypertrophic osteoarthropathy caused by a possibly pathogenic homozygous non-synonymous variant in the SLCO2A1 gene (NM_005630.3: c.289C>T, p.
Areej Albawa'neh, Mariam Ghareeb Al Mansoori, Sehriban Diab, Fatma Al Jasmi, Fatma Al Jasmi, Nadia Akawi, Nadia Akawi   +6 more
doaj   +6 more sources

Primary hypertrophic osteoarthropathy [PDF]

Научно-практическая ревматология, 2020
The article presents information about a rare hereditary disease – primary hypertrophic osteoarthropathy with autosomal dominant and autosomal recessive inheritance.
E. L. Trisvetova
doaj   +8 more sources

Primary hypertrophic osteoarthropathy – a rare cause of pain and arthritis in children. Description of 5 cases [PDF]

Central European Journal of Immunology, 2022
Primary hypertrophic osteoarthropathy (PHOA) is a very rare disease. The typical triad of symptoms, i.e. digital clubbing, periosteal bone formation with bone and joint deformities and skin hypertrophy, may be accompanied by other specific conditions. In
Joanna Wójtowicz, Beata Kołodziejczyk, Agnieszka Gazda, Piotr Gietka   +3 more
doaj   +3 more sources

Primary hypertrophic osteoarthropathy: genetics, clinical features and management [PDF]

Frontiers in Endocrinology, 2023
Primary hypertrophic osteoarthropathy (PHO) is a genetic disorder mainly characterized by clubbing fingers, pachydermia and periostosis. Mutations in the HPGD or SLCO2A1 gene lead to impaired prostaglandin E2 (PGE2) degradation, thus elevating PGE2 ...
Qi Lu, Yang Xu, Zeng Zhang, Shanshan Li, Zhenlin Zhang   +4 more
doaj   +4 more sources

Hypertrophy of the feet and ankles presenting in primary hypertrophic osteoarthropathy or pachydermoperiostosis: a case report [PDF]

Journal of Medical Case Reports, 2012
Introduction Pachydermoperiostosis or primary hypertrophic osteoathropathy is a rare genetic disease with autosomal transmission. This disorder, which affects both bones and skin, is characterized by the association of dermatologic changes (pachydermia ...
Akrout Rim, Bendjemaa Samar, Fourati Héla, Ezzeddine Mariem, Hachicha Imene, Baklouti Soufiene   +5 more
doaj   +4 more sources

Primary Hypertrophic Osteoarthropathy With Myelofibrosis. [PDF]

Cureus, 2022
Primary hypertrophic osteoarthropathy (PHO) is a rare autosomal recessive inherited multi-system disorder characterized by a triad of pachydermia, periostosis, and clubbing. PHO was revealed to be caused by the HPGD gene producing 15-prostaglandin dehydrogenase and the SLCO2A1 gene expressing one kind of prostaglandin transporter.
Yousaf M, Khan R, Akram Z, Chaudhry QU, Iftikhar R.   +4 more
europepmc   +3 more sources

Incomplete primary hypertrophic osteoarthropathy. [PDF]

BMJ Case Rep, 2020
A 63-year-old man presented with chronic multiple joint pain and swelling. The symptoms had started in adolescence, progressed for about 10–15 years, and then became constant. There was no associated morning stiffness. Symptoms suggesting any chest or abdominal disease were absent.
Prasad A, Shahi P, Sehgal A, Bhagirathi Mallikarjunaswamy M.   +3 more
europepmc   +4 more sources

Hypertrophic Osteopathy Associated With Intrathoracic Masses in 5 Dogs and Review of the Literature. [PDF]

Vet Med Int
This study describes the clinical and radiographical findings of hypertrophic osteopathy in 5 female mature adult dogs with pulmonary and mediastinal masses. Besides, the literature review from the past to today provides information about the disease.
Cetinkaya MA, Cagatay S, Pilli M, Curukoglu A, Seyrek Intas D.   +4 more
europepmc   +2 more sources

Palindromic rheumatism associated with primary hypertrophic osteoarthropathy [PDF]

Clinics, 2006
INTRODUCTION Hypertrophic osteoarthropathy (HOA) is a syndrome characterized by the triad of finger clubbing, periosteal new bone formation, skin and soft tissue changes, giving an acromegaloid look. It is present in 2 distinct syndromes: primary and secondary.
Samuel Katsuyuki Shinjo, Mauricio Levy-Neto, Eduardo Ferreira Borba   +2 more
doaj   +4 more sources

Primary hypertrophic osteoarthropathy complicated with myelofibrosis and compound heterozygous SLCO2A1 mutations: a case report and review of literature [PDF]

Frontiers in Oncology
BackgroundPrimary hypertrophic osteoarthropathy (PHO) is a rare hereditary clinical syndrome characterized by digital clubbing, periostosis, and pachydermia.
Qirui Xu, Qian Li, Jin Lu, Jin Lu, Liru Wang   +4 more
doaj   +2 more sources