Results 21 to 30 of about 1,593 (195)
Collagen‐Based Hydrogels for Cartilage Regeneration
Orthopaedic Surgery, Volume 15, Issue 12, Page 3026-3045, December 2023., 2023 This review provided an overview of the progress made in research on collagen hydrogels with chondrocytes or stem cells, comprehensively covered the research progress and clinical applications of collagen‐based hydrogels that integrated inorganic or organic materials. Cartilage regeneration remains difficult due to a lack of blood vessels.
Lihui Sun +9 more
wiley +1 more source
JBMR Plus, Volume 7, Issue 10, October 2023., 2023 ABSTRACT Degenerative osteoarthritis (OA) is recognized as an early‐onset comorbidity of X‐linked hypophosphatemia (XLH), contributing to pain and stiffness and limiting range of motion and activities of daily living. Here, we extend prior findings describing biochemical and cellular changes of articular cartilage (AC) in the phosphate‐wasting ...
Carolyn M Macica, Steven M Tommasini
wiley +1 more source
Primary hypertrophic osteoarthropathy
Научно-практическая ревматология, 2020 The article presents information about a rare hereditary disease – primary hypertrophic osteoarthropathy with autosomal dominant and autosomal recessive inheritance.
E. L. Trisvetova
doaj +1 more source
Complete form of pachydermoperiostosis with good initial response to etoricoxib: A case report
Clinical Case Reports, Volume 11, Issue 6, June 2023., 2023 X‐ray of hand showing cortical thickening and periosteal reaction in distal radius ulna and phalynges of hand of a patient with pachydermoperiostosis. Key Clinical Message Pachydermoperiostosis is a rare genetic disorder that closely resembles acromegaly. Diagnosis is usually based on distinct clinical and radiological features. Oral etoricoxib therapy
Abinash Baniya +6 more
wiley +1 more source
Nosology of genetic skeletal disorders: 2023 revision
American Journal of Medical Genetics Part A, Volume 191, Issue 5, Page 1164-1209, May 2023., 2023 Abstract The “Nosology of genetic skeletal disorders” has undergone its 11th revision and now contains 771 entries associated with 552 genes reflecting advances in molecular delineation of new disorders thanks to advances in DNA sequencing technology.
Sheila Unger +20 more
wiley +1 more source
Osteological and Biomolecular Evidence of a 7000-Year-Old Case of Hypertrophic Pulmonary Osteopathy Secondary to Tuberculosis from Neolithic Hungary [PDF]
, 2013 Seventy-one individuals from the late Neolithic population of the 7000-year-old site of Hódmezővásárhely-Gorzsa were examined for their skeletal palaeopathology.
Besra, GS +8 more
core +6 more sources
Advanced Science, Volume 10, Issue 10, April 5, 2023., 2023 The SIRT3‐medicated post‐translational acetylation of the mitochondrial respiratory chain has therapeutic potential for the treatment of osteoarthritis (OA). Mechanistically, SIRT3 directly binds and deacetylates COX4I2 to promote mitochondrial respiration activity.
Yijian Zhang +12 more
wiley +1 more source
Pierre Marie–Bamberger syndrome (secondary hypertrophic osteoarthropathy) [PDF]
International Journal of Dermatology, 2004 A 55‐year‐old man presented to our Department with a 10‐year history of coarsening of the facial features. The soft tissue of the forehead had become progressively thickened and corrugated, resulting in marked, hard‐elastic asymmetrical convolutions involving the underlying eyelids, with partial reduction of the visual field (Fig. 1a,b).
CANNAVO', Serafinella +3 more
openaire +4 more sources
High Bone Mass Disorders: New Insights From Connecting the Clinic and the Bench
Journal of Bone and Mineral Research, Volume 38, Issue 2, Page 229-247, February 2023., 2023 ABSTRACT Monogenic high bone mass (HBM) disorders are characterized by an increased amount of bone in general, or at specific sites in the skeleton. Here, we describe 59 HBM disorders with 50 known disease‐causing genes from the literature, and we provide an overview of the signaling pathways and mechanisms involved in the pathogenesis of these ...
Dylan J.M. Bergen +19 more
wiley +1 more source
CD38 Drives Progress of Osteoarthritis by Affecting Cartilage Homeostasis
Orthopaedic Surgery, Volume 14, Issue 5, Page 946-954, May 2022., 2022 CD38 is a membrane‐bound protein. This study primarily implicates CD38 as an important regulator of chondrogenic differentiation. Inhibition of CD38 demonstrated protection against cartilage degeneration, which suggests that CD38 could be a potential therapeutic target for OA.
Jin‐jin Ma +9 more
wiley +1 more source