Results 61 to 70 of about 1,826 (204)

Changes in Nucleus Pulposus Cell Atlas and the Role of SPP1 During Intervertebral Disc Degeneration: Single‐Cell Sequencing Analysis

open access: yesMediators of Inflammation, Volume 2025, Issue 1, 2025.
Background The nucleus pulposus (NP) plays a central role in the pathogenesis of intervertebral disc degeneration (IVDD); however, its internal cellular heterogeneity and molecular mechanisms have not yet been elucidated. Methods ScRNA‐seq was used to evaluate the structure of the NP at different degenerative stages in the same individual with IVDD ...
Chen Liu   +9 more
wiley   +1 more source

Radiofrequency ablation: mechanisms and clinical applications

open access: yesMedComm, Volume 5, Issue 10, October 2024.
Radiofrequency ablation (RFA) is a type of thermal ablation that induces coagulation necrosis of tumors by raising temperatures above 60°C. However, compared with complete RFA, because the ablation area cannot completely cover the entire tumor, insufficient RFA (iRFA) can lead to rapid local tumor progression, metastasis, and even further malignant ...
Jianhua Wu   +10 more
wiley   +1 more source

Association of Monocyte Count With Lung Function and Exercise Capacity Among Hospitalized COVID‐19 Survivors: A 2‐Year Cohort Study

open access: yesInfluenza and Other Respiratory Viruses, Volume 18, Issue 3, March 2024.
ABSTRACT Background Abnormal changes of monocytes have been observed in acute COVID‐19, whereas associations of monocyte count with long COVID were not sufficiently elucidated. Methods A cohort study was conducted among COVID‐19 survivors discharged from hospital. The primary outcomes were core symptoms of long COVID, distance walked in 6 min, and lung
Xiaoying Gu   +9 more
wiley   +1 more source

Real‐world data of Brazilian adults with X‐linked hypophosphatemia (XLH) treated with burosumab and comparison with other worldwide cohorts

open access: yesMolecular Genetics &Genomic Medicine, Volume 12, Issue 2, February 2024.
Abstract Background Disease‐related variants in PHEX cause XLH by an increase of fibroblast growth factor 23 (FGF23) circulating levels, resulting in hypophosphatemia and 1,25(OH)2 vitamin D deficiency. XLH manifests in early life with rickets and persists in adulthood with osseous and extraosseous manifestations.
Maria Helena Vaisbich   +10 more
wiley   +1 more source

Osteoartropatia hipertrófica secundária a neoplasia pulmonar: Relato de caso Secondary hypertrophic osteoarthropathy to lung cancer: A case report

open access: yesRevista Portuguesa de Pneumologia, 2009
A osteoartropatia hipertrófica secundária é uma alteração sistémica que acomete os ossos, as articulações e as partes moles, sendo secundária a alguma patologia intratorácica.
Angelo Ferreira da Silva Junior   +5 more
doaj  

A rare cause of digital clubbing: pachydermoperiostosis

open access: yesThe Pan African Medical Journal, 2016
A 35-year-old man of Tunisian origin complained of inflammatory arthralgia and he had noticed a progressive enlargement of his hands and feet as well as facial furrowing.
Zeineb Alaya, Walid Osman
doaj   +1 more source

Regressão do hipocratismo digital em pacientes com câncer de pulmão tratados cirurgicamente Reversal of digital clubbing in surgically treated lung cancer patients

open access: yesJornal Brasileiro de Pneumologia, 2008
OBJETIVO: Estudar, por meio de avaliações objetivas, a ocorrência de regressão do hipocratismo digital (HD) em pacientes com câncer de pulmão, tratados cirurgicamente, e revisar a literatura sobre o assunto. MÉTODOS: Sessenta e um pacientes com câncer de
José da Silva Moreira   +4 more
doaj   +1 more source

Changes in life-style after liver transplantation [PDF]

open access: yes, 1988
Sixty-five pediatric patients who received liver transplants between May 1981 and May 1984 were observed for as many as 5 years and examined for changes in life-style.
Belle, SH   +8 more
core  

Extensive periosteal new bone formation in a skeleton from post-Medieval Chichester, England: A probable case of metastatic prostatic carcinoma [PDF]

open access: yes, 2018
An elderly male skeleton from a site in Chichester, UK, was found with a widespread periosteal reaction, principally affecting the axial skeleton and the pelvis.
Rando, C, Waldron, T
core   +1 more source

“Like a virgin”: Absence of rheumatoid arthritis and treponematosis, good sanitation and only rare gout in Italy prior to the 15th century

open access: yesReumatismo, 2004
Origin of disease has special interest for rheumatologists, for whom absence of etiologic information generally mandates empirical approaches. Hypotheses have been offered that rheumatoid arthritis and syphilis were New World diseases, only transmitted ...
B.M. Rothschild, A. Coppa, PP. Petrone
doaj   +1 more source

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