Results 141 to 150 of about 197,424 (329)

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

Mediators of mechanotransduction between bone cells [PDF]

, 2009
Mechanical forces are known to regulate the function of tissues in the body, including bone. Bone adapts to its mechanical environment by altering its shape and increasing its size in response to increases in mechanical load associated with exercise, and
Komarova, S. V., Lopez, M., Miura, R. M., Qazi, S., Wall, D. J. N.   +4 more
core  

Morphology of osteoblast-like cells irradiated by low-power laser

, 1996
Ken Morimoto, Hiroo Takagi, Yasuhito Ozawa, Noriyoshi Shimizu, T Iwasawa, Yukishige Kozawa   +5 more
openalex   +2 more sources

ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α‐PADI4 Pathway to Initiate Bone Aging

Advanced Science, EarlyView.
In this study, we find CD55+ neutrophils show activated NETosis within bone marrow, induce BMSC senescence and osteogenesis inhibition, finally leading to bone aging initiation. Mechanistically, ROS synergizes with the CD55‐driven HIF1α‐PADI4 pathway to promote NETosis.
Yutong Guo, Shengjie Cui, Xi Wen, Yidi Wang, Ben Wu, Yixiang Wang, Yan Gu   +6 more
wiley   +1 more source

The Enkephalinergic Osteoblast [PDF]

Journal of Bone and Mineral Research, 1998
H, Rosen, A, Krichevsky, Z, Bar-Shavit
openaire   +2 more sources

Decoding the Cellular Heterogeneity and Malignant Progression of Human Penile Squamous Cell Carcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
Single‐cell transcriptomic and functional analyses identify SEMA3C as a key regulator of tumor progression and tumor microenvironment remodeling in penile squamous cell carcinoma. SEMA3C promotes epithelial–mesenchymal transition, tumor growth, and invasion while shaping an immunosuppressive microenvironment, highlighting its potential as a prognostic ...
Xiheng Hu, Wensheng Shi, Liang Dong, Lingjuan Huang, Xiyuan Zhang, Yiting Feng, Jie Sun, Lanlan Liu, Teng Liu, Jun Fu, Bowen Zhong, Qihao Leng, Xiaohua Wu, Minfeng Chen, Lingfang Li, Yuan Li, Xin Jin, Long Wang, Jian Cao, Xin Li, Mingzhu Yin, Xiang Chen   +21 more
wiley   +1 more source

Quantitative Analysis on Cellular Uptake of Hydroxyapatite Nanoparticles in the Primary Osteoblasts in Vitro

, 2017
Guoqiang Zhou, Sudan Liu, Wenshi Xu, Wenying Wang   +3 more
openalex   +2 more sources

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

Effects of Cyclic Strain at Focal Adhesions on Calcium Response of a Cultured Osteoblast

, 2018
K. Nagai, Toshihiko SHIRAISHI
openalex   +1 more source

The hyaluronic acid gel promotes the formation of osteoblasts mineralized nodules and fracture callus by regulating the expression of Runx2 and osteocalcin

, 2023
Jiaquan Yang, Yulian Liu, K Chen, Muzi Liu   +3 more
openalex   +2 more sources