Results 31 to 40 of about 7,611 (212)

Fixação interna de fragmento osteocondral originado de osteocondrite dissecante do joelho Internal fixation of osteochondral fragment originated fro dissecting knee osteochondritis

Acta Ortopédica Brasileira, 2008
O tratamento da osteocondrite dissecante do joelho com lesão tipo cratera associada a corpo livre intra-articular pode ser realizado pela fixação do fragmento osteocondral no seu local de origem.
Carlos Eduardo Sanches Vaz, Roberto Guarniero, Paulo José de Santana, Éden Dal Molin, Paulo Henrique Morandini   +4 more
doaj   +1 more source

A 3D‐Printed Blister Test Platform for Quantifying Biointerface Adhesion Mechanisms

Advanced Materials Interfaces, EarlyView.
A 3D‐printed blister platform enables energy‐resolved characterization of soft hydrogel–rigid interfaces. Integrating precision pressure control with hyperelastic modeling directly quantifies adhesion energy (G) and R‐curve toughening. Results reveal that modulating hydrogel concentration and surface roughness drives a tunable transition from cohesive ...
Yoontae Kim, Rahul Patil, Argyris K. Lazaris, Xinran Zhang, Stella Alimperti   +4 more
wiley   +1 more source

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

Advanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou, Yongfeng Chen, Longyou Xiao, Wei Qi, Tianshu Du, Qiang Sun, Borui Xue, Qinghe Zhao, Pengfei Xie, Zi Ye, Fei Han, Lingli Guo, Yang Jiao, Ranran Zhang, Hong Jia, Xiao Huang, Jianwei Guo, Peng Wang, Huayi Wang, Yuanrui Wang, Wenjing Chen, Haining Wu, Liumin He, Dawei Zhang   +23 more
wiley   +1 more source

Osteochondral autograft of patella. Experience up to 10 years of follow-up

Orthopaedic Journal of Sports Medicine, 2018
Introduction: The optimal treatment of an osteochondral patellar lesion remains controversial. Autologous osteochondral transplantation shows promising outcomes, although there is scarce evidence.
David Figueroa Poblete MD, Jaime Esteban Espinoza Valdés MD, Juan José Sotomayor MD, Luis O´Conell MD   +3 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Osteochondral Allograft Transplantation for Treatment of Focal Patellar Osteochondral Lesion

Arthroscopy Techniques, 2017
Patellar osteochondral lesions are common and particularly disabling injuries that can affect young and highly active patients. If enough functional impairment, ranging from difficulty climbing stairs to pain with squatting, is present, surgical ...
Marcio B. Ferrari, M.D., George Sanchez, B.S., Angela Chang, B.A., Anthony Sanchez, B.S., João L. Ellera Gomes, M.D., Ph.D., Matthew T. Provencher, M.D.   +5 more
doaj   +1 more source

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

Lateral Inverted Osteochondral Fracture of the Talus: Case Reports and Review of the Literature

Acta Clinica Croatica, 2018
Lateral inverted osteochondral fracture of the talus (LIFT) is a rare variant of stage IV osteochondral lesion of the talus (OLT), where the fragment is inverted in situ by 180°.
Andrija Jurina, Valentina Delimar, Damjan Dimnjaković, Ivan Bojanić   +3 more
doaj   +1 more source

All-Arthroscopic Osteochondral Autograft Transfer Technique for Osteochondritis Dissecans of the Talus

Arthroscopy Techniques, 2020
Juvenile osteochondritis dissecans of the talus can be a challenging condition to treat in young patients. Previously described osteochondral autograft transfer techniques for medial talar lesions have been done via open approach, often requiring medial ...
Laura Luick, M.D., Garrett Steinmetz, M.D., Amgad Haleem, M.D., Ph.D.   +2 more
doaj   +1 more source

Unorganized fibrocartilage and osseous proliferation after bone marrow stimulation for an osteochondral lesion of the talus

Journal of Cartilage & Joint Preservation, 2021
Introduction: Bone marrow stimulation (BMS) is the most commonly used treatment for an osteochondral lesion of the talus (OLT). BMS can fail, however, and may require revision surgery.
Quinten G.H. Rikken, Jari Dahmen, Gino M.M.J. Kerkhoffs, Sjoerd A.S. Stufkens   +3 more
doaj   +1 more source