Results 51 to 60 of about 4,353 (174)

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

Developmental Dynamics, Volume 255, Issue 3, Page 228-245, March 2026.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki, Rinna Kanai, Sayuri Tatsuta, Shinichi Kawaguchi, Masatsune Itoh, Shinsuke Ohba, Makoto Abe   +6 more
wiley   +1 more source

Primary Chest Wall Ewing Sarcoma With Diaphragmatic Invasion in an Adult: En‐Bloc Resection and Polypropylene Mesh Reconstruction

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Chest‐wall Ewing sarcoma (CWES) is uncommon in adults and often abuts vital thoracic structures, making R0 resection challenging despite gains with multimodal therapy. A 46‐year‐old Arab male presented with year‐long right‐sided chest pain, weight loss, and a firm mass over the lower right ribs.
Mohammad Alaa Aldakak, Ahmad Al‐Bitar, Raneem Ahmad, Hamza Alhallaq, Kinda Assoud, Hussain Chaban   +5 more
wiley   +1 more source

The Application of Orthopedic Surgical Robot‐Assisted Technology in Various Clinical Scenarios Involving Bone Tumors

Orthopaedic Surgery, Volume 18, Issue 1, Page 53-65, January 2026.
Robot‐assisted surgery facilitates precise path planning and osteotomy plane identification. With the combination of an orthopedic robot and intraoperative ultrasound or the da Vinci robot, it can enhance the precision and safety of bone tumor surgery. Furthermore, it can be integrated with patient‐specific cutting guides to minimize surgical duration.
Hanxiao Yin, Yiwei Fu, Xirenijiang Yikemu, Weihai Liu, Changye Zou, Xianbiao Xie, Zhiqiang Zhao, Puyi Sheng, Jingnan Shen, Junqiang Yin   +9 more
wiley   +1 more source

Suspected Calvarial Hyperostosis Syndrome Causing Different Ophthalmological Signs in Two Young Labrador Retrievers—Case Report

Veterinary Ophthalmology, Volume 29, Issue 1, January 2026.
ABSTRACT Objective To describe calvarial hyperostosis syndrome (CHS) as a potential and unusual cause of exophthalmos or epiphora in young dogs. Animals Studied A nine‐month‐old female intact (case 1) and a two‐year‐old male intact Labrador Retriever (case 2). Procedures Patient history, including previous treatments, was documented.
Andrea Steinmetz, Stefan Kohl
wiley   +1 more source

PIP Joint Reconstruction for Proximal Phalanx Condyle Pseudarthrosis Using an Osteochondral Graft From the Fifth Metacarpal Base: A 10‐Year Case Report

Case Reports in Orthopedics, Volume 2026, Issue 1, 2026.
Introduction Reconstruction methods for osteochondral defects of the proximal phalanx condyle are not well established, and data on long‐term clinical outcomes are limited. In many cases, joint preservation is abandoned in favor of arthrodesis or joint replacement.
Kazuki Imaishi, Makoto Motomiya, Mitsutoshi Ota, Naoya Watanabe, Keigo Yasui, Norimasa Iwasaki, Shashank Kaushik   +6 more
wiley   +1 more source

Severe Varus Deformity of the Knee due to Synovial Osteochondromatosis Treated With Megaprosthesis

Case Reports in Orthopedics, Volume 2026, Issue 1, 2026.
Synovial osteochondromatosis is a rare disease of the synovial membrane of joints that can cause severe disability and dysfunction of the joints. In this report, we present the case of a patient with severe joint destruction due to synovial osteochondromatosis treated with a megaprosthesis.
Shota Shigekiyo, Daisuke Hamada, Yasuyuki Omichi, Shunichi Toki, Yasuaki Tamaki, Keizo Wada, Toshihiko Nishisho, Koichi Sairyo, Hiroshi Takahashi   +8 more
wiley   +1 more source

Cervical Myelopathy Due to an Osteochondroma in Multiple Hereditary Exostosis

Case Reports in Orthopedics, Volume 2026, Issue 1, 2026.
Hereditary multiple exostosis is a rare genetic condition characterized by the development of multiple exostoses. Vertebral localization is rare, less than 7%. Spinal cord compression in hereditary multiple exostosis is a rare condition. We report the case of a 22‐year‐old man with cervical spinal cord compression due to an osteochondroma with ...
Géraud Garcia Segbedji, Cédric Dongmo Mayopa, Xavier Banse, Pierre-Louis Docquier, Shashank Kaushik   +4 more
wiley   +1 more source

Spontaneous resolution of a solitary osteochondroma of humerus following trauma: A case report with a review of literature

Journal of Orthopaedics, Trauma and Rehabilitation, 2019
Osteochondroma is the most common benign bone tumor; however, the natural history of the lesion is still poorly understood. Symptomatic osteochondromas are treated with excision, but more often the indications are mainly cosmetic or fear of malignant ...
Jalan Divesh, Lam Ying Lee, Wong Joyce, Yau Ching Hin Raymond   +3 more
doaj   +1 more source

Multiple Osteochondromas: Clinicopathological and Genetic Spectrum and Suggestions for Clinical Management

Hereditary Cancer in Clinical Practice, 2004
Multiple Osteochondromas is an autosomal dominant disorder characterised by the presence of multiple osteochondromas and a variety of orthopaedic deformities.
Hameetman Liesbeth, Bovée Judith VMG, Taminiau Antonie HM, Kroon Herman M, Hogendoorn Pancras CW   +4 more
doaj   +1 more source

Trigger finger due to phalangeal osteochondroma of an adult: A case report

Journal of Orthopaedic Surgery, 2020
Trigger finger is stenosing tenosynovitis that occurs in A1 pulley. It usually occurs idiopathically in patients’ 40s and 50s. On the other hand, pediatric trigger finger usually occurs before 8 years old in pediatric patients.
Hoi Young Kwon, Hong Je Kang
doaj   +1 more source