Results 181 to 190 of about 165,191 (338)

Prenatal Presentation of RMRP‐Related Skeletal Dysplasia: Clinical and Genomic Expansion

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT The RNA subunit of the mitochondrial RNA processing endoribonuclease complex is encoded by RMRP. Biallelic variants in RMRP are known for anauxetic dysplasia 1 (AD), cartilage‐hair hypoplasia (CHH), and metaphyseal dysplasia without hypotrichosis.
Radhakrishnan Periyasamy, Pascal Joset, H. E. Veenstra‐Knol, Nicole Corsten‐Janssen, Tuula Rinne, Irene Valenzuela, Marta Codina‐Solà, Carlota Rodó, Marjolaine Willems, Constance Wells, Renaud Touraine, Maayke de Koning, Gijs Santen, Iris Hollink, André Travessa, Alessandro Mauro Spinelli, Paolo Peruzzo, Moneef Shoukier, Roland Axt‐Fliedner, Thomas Menter, Gwendolin Manegold‐Brauer, Isabel Filges   +21 more
wiley   +1 more source

Osteogenesis imperfecta and dentinogenesis imperfecta: associated disorders

, 2015
This paper presents a review of dentinogenesis imperfecta occurring in patients with osteogenesis imperfecta. The systemic manifestations and the oral aspects of dentinogenesis imperfecta in osteogenesis imperfecta are discussed, and an illustrative case
Tenuta, L. M. A., Vieira, A. L. F., Machado, M. A. D. M., Rios, D.   +3 more
core  

Engineered 3D Fibronectin‐Based Environments Modulate the Pathogenic Profile of Arthritic Synovial Fibroblasts

Advanced NanoBiomed Research, EarlyView.
Fibroblast behavior is shaped by the surrounding microenvironment, yet conventional culture systems often fail to capture disease‐relevant phenotypes. Here, platform‐dependent responses of healthy and arthritic synovial fibroblasts are examined across 2D and 3D culture systems. Distinct inflammatory and proliferative signatures emerge, highlighting how
Aneesah Khan, Piaopiao Pan, Yanling Lan, Çağlar Çi̇l, Julia Isakova, Yilin Wang, Theodora Rogkoti, Thanutchaporn Sartyoungkul, James F. C. Windmill, Jonathan William, Manuel Salmeron‐Sanchez, Margaret H. Harnett, Oana Dobre, Miguel A. Pineda   +13 more
wiley   +1 more source

Methacrylated Gelatin and Graphene Oxide Hybrid Hydrogels Composed‐Bioinks for 3D Tissue Engineering

Advanced NanoBiomed Research, EarlyView.
Bioinks made from hydrogels, such as methacrylated gelatin (GelMA), serve as the base material for bioprinted tissues, offering versatility and biocompatibility for a range of applications. Additional components however are still needed to improve functionality and mechanical stability of hydrogels. One of these components is graphene oxide (GO), added
Wanessa S. Mota, Erika S. Lisboa, Victoria L. S. dos Santos, Carine Serafim, Maria L. F. Bezerra, Thais F. R. Alves, Marco V. Chaud, Frederico S. Martins, Juliana C. Cardoso, Eliana B. Souto, Patrícia Severino   +10 more
wiley   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source

First reports on the relationship between the eggshell and bone mineralization in Rhinoclemmys punctularia punctularia embryos

The Anatomical Record, EarlyView.
Abstract Composed of various minerals, the eggshell provides ideal conditions for embryonic development, and understanding its composition and structure is essential for clarifying its relationship with bone formation. This study characterized the structure and mineral profile of the Rhinoclemmys punctularia punctularia eggshell in relation to ...
Igor Mathias Trindade Lemos, Deise Cardoso de Lima, Antônio Basílio Guerreiro Júnior, Brenda Stefany dos Santos Braga, Antônio Messias Costa, Ana Cássia Sarmento Ferreira, Maria Auxiliadora Ferreira, Verônica Oliveira‐Bahia, Diva Anelie de Araújo Guimarães   +8 more
wiley   +1 more source

Promotion of in vivo degradability, vascularization and osteogenesis of calcium sulfate-based bone cements containing nanoporous lithium doping magnesium silicate

, 2017
Liehu Cao,1,* Weizong Weng,1,* Xiao Chen,1,* Jun Zhang,1 Qirong Zhou,1 Jin Cui,1 Yuechao Zhao,1 Jung-Woog Shin,2 Jiacan Su1 1Department of Orthopaedics Trauma, Changhai Hospital, Second Military Medical University, Shanghai, People’s Republic of ...
Cao L, Zhou Q, Zhang J, Weng W, Cui J, Shin J, Chen X, Su J, Zhao Y   +8 more
core  

Cortical bone geometry and static gravitational loads in neosauropod dinosaurs: Implications for biomechanical constraints on terrestrial gigantism

The Anatomical Record, EarlyView.
Abstract Sauropod dinosaurs achieved unprecedented terrestrial gigantism, raising questions about the biomechanical limits of bone under extreme gravitational loads. We estimated static gravitational pressures (Pg) on appendicular cortical bone in neosauropods, including diplodocoids, brachiosaurids, and titanosaurs.
Tito Aureliano, Aline M. Ghilardi, Holly N. Woodward, Horácio W. L. Alves, Guilherme M. Sipahi   +4 more
wiley   +1 more source

Sheep Horn Development Revealed by Multi‐Tissue and Cross‐Species Transcriptomic Analysis

Animal Research and One Health, EarlyView.
Multi‐tissue and cross‐species transcriptomics with allele‐specific expression show sheep horns are a composite organ integrating epidermal and osteogenic programs. Conserved horn gene modules and cis‐regulatory variation fine‐tune expression networks underlying horn development and size (small scurs vs. large spiral horns).
Hao Li, Yuchen He, Yangshuo Hu, Naominggaowa, Huaiqiang Yang, Zhu Meng, Fei Liu, Shiwen Zhang, Yi Jin, Mingxing Chu, Zhangyuan Pan   +10 more
wiley   +1 more source

Total Cranial Vault Remodeling Using Multidirectional Cranial Distraction Osteogenesis in Craniosynostosis. [PDF]

Plast Reconstr Surg Glob Open
Raposo-Amaral CE, Raposo-Amaral CA, Ghizoni E.   +2 more
europepmc   +1 more source