Results 91 to 100 of about 15,355 (222)

Computed tomography identifies the proximodorsomedial subchondral bone of equine central tarsal bones as a predilection site for sclerosis, demineralisation and associated fractures

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The distribution pattern of central tarsal bone (CTB) changes has not been described, except for slab‐ and dorsomedial–plantarolateral fractures. Objectives To describe CTB changes in CT and document their distribution and associations. Study Design Retrospective case series.
Sandra Campana   +3 more
wiley   +1 more source

Glenoid failure in Total Shoulder Arthroplasty

open access: yes, 2011
Compared to hip and knee, anatomic shoulder arthroplasty is relatively poorly understood, underdeveloped and reported loosening rates are very high, the common cause of failure being glenoid aseptic loosening.
Gregory, Thomas Maurice Stewart   +1 more
core   +1 more source

Biological response to prosthetic debris. [PDF]

open access: yes, 2015
Joint arthroplasty had revolutionized the outcome of orthopaedic surgery. Extensive and collaborative work of many innovator surgeons had led to the development of durable bearing surfaces, yet no single material is considered absolutely perfect ...
Bitar, Diana, Parvizi, Javad
core   +2 more sources

Interactions between small leucine‐rich proteoglycans and proteases: implications for tissue homeostasis and pathology

open access: yesThe FEBS Journal, EarlyView.
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki   +4 more
wiley   +1 more source

Pediatric Hip Disorders

open access: yesJournal of the Korean Society of Radiology
Developmental dysplasia of the hip is a condition characterized by hip joint instability due to acetabular dysplasia in infancy, necessitating precise ultrasound examination. Legg- Calvé-Perthes disease is caused by a temporary disruption in blood flow
Seunghyun Lee   +4 more
doaj   +1 more source

Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts

open access: yesBreast Cancer Research, 2018
Background Bone is one of the most frequent metastatic sites of advanced breast cancer. Current therapeutic agents aim to inhibit osteoclast-mediated bone resorption but only have palliative effects.
Xuxiang Liu   +8 more
doaj   +1 more source

Bone morphogenetic proteins, breast cancer, and bone metastases: striking the right balance [PDF]

open access: yes, 2017
Bone morphogenetic proteins (BMPs) belong to the TGF-β super family, and are essential for regulation of foetal development, tissue differentiation and homeostasis, and a multitude of cellular functions.
Hargest, Rachel   +4 more
core   +1 more source

Diagnosing Systemic Mastocytosis: State of the Art

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT With the advent of effective multikinase and selective tyrosine kinase inhibitors in systemic mastocytosis, diagnosing this rare disease has been critical to improving patient morbidity and mortality. This state‐of‐the‐art review interprets the international diagnostic criteria, including differences between the WHO 5th edition classification ...
Anton Rets, Tracy I. George
wiley   +1 more source

Effect of Low-magnitude, High-frequency Vibration on Osteocytes in the Regulation of Osteoclasts [PDF]

open access: yes, 2010
Osteocytes are well evidenced to be the major mechanosensor in bone, responsible for sending signals to the effector cells (osteoblasts and osteoclasts) that carry out bone formation and resorption. Consistent with this hypothesis, it has been shown that
Al-Dujaili, Saja   +5 more
core   +2 more sources

Radiographic Analysis of MRONJ in Osteoporotic and Oncologic Patients on Bisphosphonates or Denosumab

open access: yesOral Diseases, EarlyView.
ABSTRACT Introduction Medication‐Related Osteonecrosis of the Jaw (MRONJ) is a severe adverse effect of antiresorptive and antiangiogenic treatment, primarily in osteoporotic and oncologic patients. The disease is characterized by persistent jawbone necrosis that results in significant impairment of the quality of life of involved patients.
Omar Ghanaiem   +2 more
wiley   +1 more source

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