Results 101 to 110 of about 15,355 (222)

Customized Metal 3D Printed Total Wrist Prosthesis in the Treatment of Severely Destroyed Wrist: Design Rationale and Clinical Applications

Orthopaedic Surgery, Volume 17, Issue 5, Page 1536-1546, May 2025.
Four patients with severe wrist destruction from various causes were treated with customized 3D‐printed prostheses. In addition to the specific articular surface matching their original radiocarpal joint, two innovative proximal component designs were created to address different bone defects.
Qipei Wei, Chang Liu, Shanlin Chen, Min Liu   +3 more
wiley   +1 more source

RANK and RANK ligand expression in primary human osteosarcoma

Journal of Bone Oncology, 2015
Receptor activator of nuclear factor kappa-B ligand (RANKL) is an essential mediator of osteoclast formation, function and survival. In patients with solid tumor metastasis to the bone, targeting the bone microenvironment by inhibition of RANKL using ...
Daniel Branstetter, Kathy Rohrbach, Li-Ya Huang, Rosalia Soriano, Mark Tometsko, Michelle Blake, Allison P. Jacob, William C. Dougall   +7 more
doaj   +1 more source

Molekulare Signalwege der aseptischen Endoprothesenlockerung [PDF]

, 2017
Die Behandlung von immobilisierenden degenerativen und entzündlichen Gelenkerkrankungen mit der Implantation von Endoprothesen ist ein großer Erfolg und Fortschritt in der Medizin und hat stark zur Verbesserung der Lebensqualität der betroffenen ...
Drees, Philipp, Eckardt, Anke, Gay, Renate E., Gay, Steffen, Huber, Lars C.   +4 more
core  

Therapeutic Strategies and Clinical Outcomes of Infections Following Anterior Cruciate Ligament Reconstruction: A Narrative Review

Orthopaedic Surgery, EarlyView.
ACL reconstruction‐associated infections threaten graft integrity and joint function. This review summarizes patient‐related risk factors, approaches, and treatment strategies, with emphasis on early recognition and preventive measures such as vancomycin presoaking.
Shaoli Zhang, Jue Gong
wiley   +1 more source

Molecular alterations that drive breast cancer metastasis to bone. [PDF]

, 2015
Epithelial cancers including breast and prostate commonly progress to form incurable bone metastases. For this to occur, cancer cells must adapt their phenotype and behaviour to enable detachment from the primary tumour, invasion into the vasculature ...
Friedrich RE, Karakosta A, Kim MS, Liang Z, Mackinder MA, Pé, Paget S, Powell GJ, Singh RK, Taichman RS, Takayama S, van der Pluijm G, Vesuna F   +12 more
core   +1 more source

Engineered surface strategies to manage dental implant‐related infections

Periodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza, Bruna E. Nagay, Rodrigo Martins, Martinna Bertolini, Jamil A. Shibli, Conrado Aparicio, Magda Feres, Valentim A. R. Barão   +7 more
wiley   +1 more source

Locally advanced sinonasal squamous cell carcinoma presenting as oral pain in a dog

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract An 11‐year‐old, female, spayed, mixed breed dog was presented with a 1‐month history of oral pain. No major physical abnormalities were reported. A comprehensive oral examination was recommended. At intubation, temporomandibular joint crepitus and decreased range of motion were observed.
Jocosa Yasenchack, Hamideh Esmaeilzadeh, Carolina Panisello, Eric Hostnik, Laura E. Selmic   +4 more
wiley   +1 more source

Tuning and validation of a virtual mechanical testing pipeline for condylar stress fracture risk assessment in Thoroughbred racehorses

Royal Society Open Science
Condylar stress fracture of the third metacarpal/metatarsal bone (MC3/MT3) in Thoroughbred racehorses is a common catastrophic injury, putting both the racehorse and the jockey at risk.
Soroush Irandoust, Chris Whitton, Corinne Henak, Peter Muir   +3 more
doaj   +1 more source

Photon‐Counting CT for Diagnosing Vertical Root Fractures in Teeth With Metal Posts: An Ex Vivo Comparative Analysis With Four CBCT Devices

International Endodontic Journal, Volume 59, Issue 4, Page 718-727, April 2026.
ABSTRACT Objective Photon‐counting computed tomography (PCCT) represents a major innovation in X‐ray detection technology, offering improved signal efficiency and reduced electronic noise compared with cone‐beam computed tomography (CBCT), which can enhance image quality.
Renata M. S. Leal, Fernanda B. Fagundes, Maria F. S. A. Bortoletto, Samuel C. Kluthcovsky, Walter Coudyzer, Bruno C. Cavenago, Reinhilde Jacobs, Rocharles Cavalcante Fontenele   +7 more
wiley   +1 more source

Porphyromonas gingivalis–Derived Virulence Lipids Accelerate Osteoclastogenesis Independently of High Mobility Group Box Protein‐1 Canonical Signaling

Molecular Oral Microbiology, Volume 41, Issue 2, Page 85-93, April 2026.
ABSTRACT Periodontal bacterial pathogen‐associated molecular patterns (PAMPs) and damage‐associated molecular patterns (DAMPs) accelerate inflammatory osteoclastogenesis, resulting in alveolar bone loss. The core PAMP and DAMP prototype molecules are periodontal bacterium Porphyromonas gingivalis–derived virulence lipids, for example, phosphoglycerol ...
Chiaki Yamada, Gang Peng, James A. Johnson Jr., Amilia Nusbaum, Natasha Sanz, Hawra AlQallaf, Frank Nichols, Alexandru Movila   +7 more
wiley   +1 more source