Results 31 to 40 of about 24,690 (186)

An assessment of the clinical relevance of coracoid graft osteolysis following the Latarjet procedure: a clinical and radiological review

JSES International
Background: The Latarjet procedure was developed for the treatment of anterior shoulder instability in young, high-demand patients with attritional glenoid bone loss, whose risk of redislocation following primary dislocation may exceed 90%.
Ryan S. Ting, Bob Jang, BMed, FRACS (Orth), FAOrthA, Nicholas Murray, MBChB, FRCSEd (Tr&Orth), Tiffany G. Williams, BSc (Hons), MD, Isabella L. Kang, Yon Su, Tam Anh Nguyen, William E. Ridley, BMed, Blake R. Manowski, Michelle Caudwell, MBBS, FRACS (Orth), FAOrthA, Linda Martin, MD, FAAOS, John N. Trantalis, MBBS (Hons), FRACS (Orth), FAOrthA   +11 more
doaj   +1 more source

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

Advanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang, Rui Zhang, Xiao‐Min Yue, Jie Zhou, Yu‐Fan Huang, Rong Meng, Yu‐Li Wang, Xiao‐Qing Li   +7 more
wiley   +1 more source

Clinical course and factors associated with progressive acro-osteolysis in early systemic sclerosis: a retrospective cohort study

Scientific Reports
To examine clinical course of early systemic sclerosis (SSc) and identify factors for progression of acro-osteolysis by a retrospective cohort study.
Punthip Thammaroj, Prathana Chowchuen, Chingching Foocharoen   +2 more
doaj   +1 more source

Cementless Hip Implants: History and Current Status of the Issue

Travmatologiâ i Ortopediâ Rossii, 2020
Background. Total hip arthroplasty is an effective type of surgery with excellent survival rates of modern implants. From the very beginning of the widespread introduction of total hip arthroplasty, the cement technique of components fixing prevailed ...
I. I. Shubnyakov, A. Riahi, M. I. Shubnyakov, A. O. Denisov, I. E. Khujanazarov, R. M. Tikhilov   +5 more
doaj   +1 more source

Gorham's Syndrome Associated with Chiari I Malformation and Recurrent Meningitis without Fistula: Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2018
Gorham’s syndrome is a rare osteolytic disease in which progressive and spontaneous resorption of bone occurs. We present a case of a boy who presented with Chiari I malformation and recurrent meningitis without fistula.
Fernando Antônio Oliveira Costa, Othello Moreira Fabião Neto, Frederico Lima Gibbon, Guilherme Gago Silva, Luciana Azambuja Al Alam   +4 more
doaj   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source

Gorham-Stout Disease with Multiple Bone Involvement—Challenging Diagnosis of a Rare Disease and Literature Review

Medicina, 2021
Gorham-Stout disease is a rare disorder, which may result in a poor prognosis. This disease, a rare lymphangiomatosis, is defined by progressive bone disappearance due to massive unicentric and multicentric osteolysis. Osteolytic lesions of the spine and
Alina Momanu, Lavinia Caba, Nicoleta Carmen Gorduza, Oana Elena Arhire, Alina Delia Popa, Victor Ianole, Eusebiu Vlad Gorduza   +6 more
doaj   +1 more source

Osteolysis and cancer [PDF]

Journal of Clinical Investigation, 2001
Bone is a highly hospitable environment for colonization and growth of metastatic tumors, and some of the most common human malignancies, notably breast cancer and prostate cancer, have a strong propensity to produce skeletal metastases (1). Tumor cells, in turn, can produce a spectrum of skeletal manifestations which spans diffuse osteopenia, focal ...
openaire   +2 more sources

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source