Results 71 to 80 of about 24,690 (186)

Fatal spinal cord compression in a horse with chronic actinobacterial cranial nuchal bursitis

open access: yesEquine Veterinary Education, EarlyView.
Summary A 14‐year‐old warmblood gelding was managed for waxing and waning cranial nuchal bursitis for 2 years. Intensive medical and surgical management was not curative, and the patient was subjected to euthanasia after becoming acutely recumbent. Ante‐mortem and post‐mortem next generation sequencing of bursal tissue and post‐mortem conventional PCR ...
H. Mesch   +4 more
wiley   +1 more source

Computed tomography identifies the proximodorsomedial subchondral bone of equine central tarsal bones as a predilection site for sclerosis, demineralisation and associated fractures

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The distribution pattern of central tarsal bone (CTB) changes has not been described, except for slab‐ and dorsomedial–plantarolateral fractures. Objectives To describe CTB changes in CT and document their distribution and associations. Study Design Retrospective case series.
Sandra Campana   +3 more
wiley   +1 more source

Interactions between small leucine‐rich proteoglycans and proteases: implications for tissue homeostasis and pathology

open access: yesThe FEBS Journal, EarlyView.
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki   +4 more
wiley   +1 more source

Diagnosing Systemic Mastocytosis: State of the Art

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT With the advent of effective multikinase and selective tyrosine kinase inhibitors in systemic mastocytosis, diagnosing this rare disease has been critical to improving patient morbidity and mortality. This state‐of‐the‐art review interprets the international diagnostic criteria, including differences between the WHO 5th edition classification ...
Anton Rets, Tracy I. George
wiley   +1 more source

Puerarin Exerts Protective Effects on Wear Particle-Induced Inflammatory Osteolysis

open access: yesFrontiers in Pharmacology, 2019
Wear particle-stimulated inflammatory bone destruction and the consequent aseptic loosening remain major postoperative problems for artificial joints. Studies have indicated that puerarin promotes osteogenesis and alleviates lipopolysaccharide-induced ...
Chao Yang   +6 more
doaj   +1 more source

Radiographic Analysis of MRONJ in Osteoporotic and Oncologic Patients on Bisphosphonates or Denosumab

open access: yesOral Diseases, EarlyView.
ABSTRACT Introduction Medication‐Related Osteonecrosis of the Jaw (MRONJ) is a severe adverse effect of antiresorptive and antiangiogenic treatment, primarily in osteoporotic and oncologic patients. The disease is characterized by persistent jawbone necrosis that results in significant impairment of the quality of life of involved patients.
Omar Ghanaiem   +2 more
wiley   +1 more source

Customized Metal 3D Printed Total Wrist Prosthesis in the Treatment of Severely Destroyed Wrist: Design Rationale and Clinical Applications

open access: yesOrthopaedic Surgery, Volume 17, Issue 5, Page 1536-1546, May 2025.
Four patients with severe wrist destruction from various causes were treated with customized 3D‐printed prostheses. In addition to the specific articular surface matching their original radiocarpal joint, two innovative proximal component designs were created to address different bone defects.
Qipei Wei   +3 more
wiley   +1 more source

Therapeutic Strategies and Clinical Outcomes of Infections Following Anterior Cruciate Ligament Reconstruction: A Narrative Review

open access: yesOrthopaedic Surgery, EarlyView.
ACL reconstruction‐associated infections threaten graft integrity and joint function. This review summarizes patient‐related risk factors, approaches, and treatment strategies, with emphasis on early recognition and preventive measures such as vancomycin presoaking.
Shaoli Zhang, Jue Gong
wiley   +1 more source

Engineered surface strategies to manage dental implant‐related infections

open access: yesPeriodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza   +7 more
wiley   +1 more source

Locally advanced sinonasal squamous cell carcinoma presenting as oral pain in a dog

open access: yesVeterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract An 11‐year‐old, female, spayed, mixed breed dog was presented with a 1‐month history of oral pain. No major physical abnormalities were reported. A comprehensive oral examination was recommended. At intubation, temporomandibular joint crepitus and decreased range of motion were observed.
Jocosa Yasenchack   +4 more
wiley   +1 more source

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