Results 71 to 80 of about 26,453 (213)

Pharmacodynamic Exposure–Response Analysis of Fracture Count Data Following Treatment with Burosumab in Patients with XLH

open access: yesThe Journal of Clinical Pharmacology, Volume 65, Issue 2, Page 253-260, February 2025.
Abstract X‐linked hypophosphatemia (XLH) is a rare genetic disorder caused by excessive fibroblast growth factor 23 (FGF23), leading to low serum phosphate levels resulting in increased risk of fractures and pseudofractures. Burosumab is indicated for the treatment of XLH.
Krina Mehta   +7 more
wiley   +1 more source

Potential Health Impacts, Treatments, and Countermeasures of Martian Dust on Future Human Space Exploration

open access: yesGeoHealth, Volume 9, Issue 2, February 2025.
Abstract The challenges of human space exploration produce some of humanity's greatest technological and scientific advances, not excluding innovations in medicine. The microgravity environment causes a host of physiological changes, and exposure to dust on the Moon caused considerable pulmonary distress to astronauts during the Apollo missions. As the
Justin L. Wang   +7 more
wiley   +1 more source

Tumor-induced osteomalacia

open access: yesOsteoporosis and Sarcopenia, 2018
Tumor-induced osteomalacia (TIO), also known as oncogenic osteomalacia, is a rare paraneoplastic syndrome characterized by hypophosphatemia resulting from decreased tubular phosphate reabsorption, with a low or inappropriately normal level of active ...
Zinan Yin, Juan Du, Fan Yu, Weibo Xia
doaj  

Atraumatic femoral neck fracture secondary to prolonged lactation induced osteomalacia

open access: yesMedical Journal of Dr. D.Y. Patil University, 2013
Presenting a case of atraumatic fracture neck femur secondary to 2 years of prolonged lactation. A 26-year-old lactating mother presented with pain in left hip from last 12 months. She was apparently alright before and during pregnancy.
Dhammapal Sahebrao Bhamare   +4 more
doaj   +1 more source

Hypophosphatemic osteomalacia due to cadmium toxicity in silverware industry: A curious case of aches and pains

open access: yesJournal of Family Medicine and Primary Care
Hypophosphatemic osteomalacia in an adult often gives clinical diagnostic challenges. Usually, they are caused by either tumor-induced osteomalacia or due to genetically mediated hypophosphatemia, particularly X-linked hypophosphatemia.
Ayan Roy   +3 more
doaj   +1 more source

Celiac disease causing severe osteomalacia: an association still present in Morocco!

open access: yesThe Pan African Medical Journal, 2014
Celiac disease (CD), a malabsorption syndrome caused by hypersensitivity to gliadin fraction of gluten. CD can manifest with classic symptoms; however, significant myopathy and multiple fractures are rarely the predominant presentation of untreated ...
Latifa Tahiri   +4 more
doaj   +1 more source

Frequency of Osteomalacia in Elderly Patients With Hip Fracture

open access: yesJournal of Orthopedic and Spine Trauma, 2015
Background: Osteomalacia represents a risk factor for hip fracture (HF), which is one of the most common and costly injuries in elderly. Objectives: This study was performed to determine the frequency of histopathologic and laboratory osteomalacia in ...
Taghi Baghdadi   +4 more
doaj  

Hypophosphatemic rickets: A case of recurrent pathological fractures

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
Introduction: Renal phosphate-wasting disorders are the most common form of hereditary rickets and osteomalacia in western countries, but are rarely reported in India. Therefore, we report here a case of hypophosphatemic rickets.
Arjun Baidya   +3 more
doaj   +1 more source

Vitamin D deficiency presenting like hypophosphatemic osteomalacia

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
Introduction: Osteomalacia is one of the most common osteometabolic diseases. It is typically caused by lack of vitamin D and is characterized by mineralization deficiency of the osteoid matrix in the cortical and trabecular bone.
Rajneesh Mittal   +2 more
doaj   +1 more source

Vitamin D Deficiency in Turkish Women

open access: yesTürk Osteoporoz Dergisi, 2003
Osteomalacia is a metabolic bone disease caused by deficiency of vitamin D or its active metabolites. Since poor exposure to sunlight is one of the most common causes of osteomalacia, the disease seems to be rare in countries receiving adequate sunlight.
Kıymet İkbal Karadavut   +2 more
doaj  

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