Repurposing Metformin to Promote Fracture Callus Maturation via AMPK‐Driven Metabolic Activation
ABSTRACT Femoral shaft fractures cause prolonged disability, and therapies that accelerate bone repair remain limited. Repurposing clinically approved drugs that target biological bottlenecks in healing is a promising strategy. This study investigated whether systemic metformin administration, an anti‐diabetic medication with known metabolic regulatory
Vasyl Pastukh +7 more
wiley +1 more source
Hip disarticulation and external hemipelvectomy for infectious indications: a systematic review. [PDF]
Chernov D +7 more
europepmc +1 more source
Management of hematogenous osteomyelitis in children in Douala, Cameroon: diagnostic challenges, complications, and perspectives for improvement. [PDF]
Mantho Fopa P +8 more
europepmc +1 more source
Destructive Mold Osteomyelitis of the Wrist Caused by <i>Scedosporium apiospermum</i>-A Case Report. [PDF]
Bo C +8 more
europepmc +1 more source
Chronic Osteomyelitis and Pathologic Fractures Following Radiation-Treated Sarcoma Complicated by Knee Effusion: A Case Report. [PDF]
Syed W +3 more
europepmc +1 more source
Seeding the Spine: Salmonella Java Discitis and Osteomyelitis After Traveller's Bacteraemia. [PDF]
Abdelgabar N +3 more
europepmc +1 more source
Current trends in burden and management of pediatric osteomyelitis in the African continent: a systematic review of the last decade. [PDF]
Ipomai V +7 more
europepmc +1 more source
Osteomyelitis is an ancient disease with varied pathophysiology. The several clinical syndromes associated with bone infection have specific clinical presentations and microbiology. Successful recognition and management of the disease requires a knowledge of these mechanisms and the organisms most common in each.
Dragomirov, Dragomir +3 more
exaly +4 more sources

