Results 41 to 50 of about 89,329 (283)

Acute exacerbation of chronic osteomyelitis triggered by aggravation of type 2 diabetes mellitus: a case report

Journal of Medical Case Reports, 2019
Background Osteomyelitis is an infection in a bone. Acute osteomyelitis is observed mainly in the long leg bones of children and is usually treated with antibiotics.
Shintaro Irie, Takatoshi Anno, Fumiko Kawasaki, Ryo Shigemoto, Hideaki Kaneto, Kohei Kaku, Niro Okimoto   +6 more
doaj   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source

What is the burden of osteomyelitis in Germany? An analysis of inpatient data from 2008 through 2018

BMC Infectious Diseases, 2021
Background The epidemiology of osteomyelitis in Germany is unknown, which makes it difficult to estimate future demands. Therefore, we aimed to analyse how the numbers of cases have developed over the last decade as a function of osteomyelitis subtype ...
Nike Walter, Susanne Baertl, Volker Alt, Markus Rupp   +3 more
doaj   +1 more source

Photothermal–Immunomodulatory Hydrogel Reinforced by Ti3C2/ZnAl‐LDH Nanoplatform for Eradicating MRSA and Promoting Diabetic Wound Healing

Advanced Science, EarlyView.
A NETs‐inspired Ti3C2/LDH hydrogel integrates trapping, ROS boosting, and M2‐immunomodulation for MRSA‐infected wound repair. ABSTRACT MRSA infections give rise to chronic cutaneous and advance into profound tissue invasions, including osteomyelitis and sepsis—conditions for which existing clinical interventions offer only limited efficacy. The utility
Qiang Shi, Renliang Zhao, Jia Wang, Zhenchen Xiong, Xiangtian Deng, Cheng Zheng, Wenzhi Zhang   +6 more
wiley   +1 more source

Distally based sural flaps for soft tissue defects following traumatic osteomyelitis of lower leg and foot

Scientific Reports
This retrospective study aimed to determine the incidence and risk factors for osteomyelitis recurrence and present our experiences in treating traumatic osteomyelitis in the lower leg and foot.
Shunhong Luo, Yingliang Jiang, Zhonggen Dong, Xiao Peng, Shimu Shi, Zhaobiao Luo, Shibin Tao, Jianwei Wei   +7 more
doaj   +1 more source

Dual‐Anchored Clickable Peptide via SPAAC for Gelatinase‐Responsive Antibacterial and Osteogenic Functions on Titanium Implants

Advanced Science, EarlyView.
To address the infection‐associated orthopedic implant failures, this study presents a gelatinase‐responsive antibacterial titanium implant (Ti‐Dual) featuring a dual‐anchored fusion peptide containing antibacterial (HHC36) and osteogenic (RGD) domains connected by a cleavable GPLGV linker.
Ru Zhong, Hang Zhou, Chenyang Ye, Lei Chu, Lin Wang, Yingjun Wang   +5 more
wiley   +1 more source

PECULIAR IMMUNOLOGICAL PROPERTIES OF CHRONIC POSTTRAUMATIC OSTEOMYELITIS

Travmatologiâ i Ortopediâ Rossii, 2012
A comparative study of cellular immunity parameters was performed in patients with long bone chronic posttraumatic osteomyelitis in regard to osteomyelitis stages.
M. V. Chepeleva, N. M. Klyushin
doaj   +1 more source

Bacillus Calmette-Guérin (BCG) osteomyelitis among children: Experience in a single tertiary center in central Taiwan

Journal of Microbiology, Immunology and Infection, 2022
Background: The insidious nature of BCG-osteomyelitis makes it challenging for clinicians to detect it early on. Methods: This 12-year retrospective analysis was conducted at a single tertiary hospital in central Taiwan.
Yan Yi Low, Yu-Lung Hsu, Jiun-An Chen, Hsiu-Mei Wei, Huan-Cheng Lai, Yu-Ting Chiu, Chien-Chung Kuo, Hsiao-Chuan Lin, Kao-Pin Hwang   +8 more
doaj   +1 more source

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

Advanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin, Si‐ying He, Ting‐hui Xiao, Da‐mao Dai, Xin‐jia Hu, Nan Jiang   +5 more
wiley   +1 more source

Malignant transformation in chronic osteomyelitis

Revista Brasileira de Ortopedia
INTRODUCTION: Carcinomatous degeneration is a rare and late complication developing decades after the diagnosis of chronic osteomyelitis. OBJECTIVES: To present the results from a retrospective study of six cases of squamous cell carcinoma arising ...
Diogo Lino Moura, Rui Ferreira, António Garruço   +2 more
doaj   +1 more source