Results 51 to 60 of about 82,122 (309)
Advanced Science, EarlyView.ABSTRACT Bacterial wound infections, particularly those caused by Escherichia coli and Pseudomonas aeruginosa, are difficult to treat due to biofilm formation, multidrug resistance, and chronic inflammation. Here, we report a multifunctional nanoplatform based on a surface‐enhanced Raman scattering (SERS) probe that enables simultaneous photodynamic ...
Hanbin Deng +6 more
wiley +1 more source
Antibiotics In Osteomyelitis [PDF]
, 2018 The use of antibiotics for the treatment of osteomyelitis is still a major challenge today. A lot of research is still being done to overcome this problem. However, more can be done if not for the high cost.
Sri Tharan, Kavindrren
core
Frontiers in MicrobiologyBackgroundAcute hematogenous osteomyelitis is the most common form of osteomyelitis in children. In recent years, the incidence of osteomyelitis has been steadily increasing.
Yingtu Xia +3 more
doaj +1 more source
Real-World Use of Oritavancin for the Treatment of Osteomyelitis
Drugs - Real World Outcomes, 2020 Osteomyelitis is a difficult-to-treat disease that can require both surgical debridement and a prolonged course of antimicrobial therapy. Current standard of care for the antimicrobial treatment of osteomyelitis is fraught with multiple challenges and ...
Patrick J. Scoble +2 more
doaj +1 more source
Journal of Orthopaedic Surgery and Research, 2021 Background Free flaps have been a useful modality in the management of lower extremity osteomyelitis particularly in limb salvage. This study aimed to determine the factors affecting the outcome of free flap reconstruction in the treatment of ...
Duy Quang Thai +3 more
doaj +1 more source
Advanced Science, EarlyView.Through AI‐assisted screening from FDA‐approved API to overcome the limitations of bacterial osteomyelitis treatment, glycyrrhizic acid and simvastatin are identified as a multifunctional combination capable of self‐assembling into mechanism‐targeting nanocrystals that effectively neutralize reactive oxygen species, suppress M1 macrophage polarization,
Yu Han +11 more
wiley +1 more source
, 2016 Osteomyelitis is an infectious process that affects any part of the bone, including the periosteum, the cortex, or the marrow. It most often occurs in the lower extremities and can be an acute, subacute, or chronic process.
Lisa A. Steiner
core +1 more source
Advanced Science, EarlyView.A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang +14 more
wiley +1 more source
What is the burden of osteomyelitis in Germany? An analysis of inpatient data from 2008 through 2018
BMC Infectious Diseases, 2021 Background The epidemiology of osteomyelitis in Germany is unknown, which makes it difficult to estimate future demands. Therefore, we aimed to analyse how the numbers of cases have developed over the last decade as a function of osteomyelitis subtype ...
Nike Walter +3 more
doaj +1 more source