Results 41 to 50 of about 82,122 (309)

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

open access: yesAdvanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo   +7 more
wiley   +1 more source

Vertebral osteomyelitis and discitis [PDF]

open access: yes, 2012
[extract] INTRODUCTION — Vertebral osteomyelitis was recognized as a distinct clinical entity by Hippocrates and Galen. Prior to the discovery of antibiotics, vertebral osteomyelitis was fatal in approximately 25 percent of affected patients [1 ...
Sexton, Daniel J., McDonald, Malcolm
core  

Acute exacerbation of chronic osteomyelitis triggered by aggravation of type 2 diabetes mellitus: a case report

open access: yesJournal of Medical Case Reports, 2019
Background Osteomyelitis is an infection in a bone. Acute osteomyelitis is observed mainly in the long leg bones of children and is usually treated with antibiotics.
Shintaro Irie   +6 more
doaj   +1 more source

E.coli Associated Extensive Bilateral Maxillary Osteomyelitis: A Rare Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2013
With the advent of broad spectrum antibiotics, chronic osteomyelitis of jaw, especially of maxilla, has become a rare lesion. Osteomyelitis of jaw is associated with a complex microbiota, the most common oral microorganism being, Staphylococcus sp ...
Subrat Kumar Padhiary   +4 more
doaj   +1 more source

Chronic Osteomyelitis

open access: yesCurrent Infectious Disease Reports, 2012
Chronic osteomyelitis is a multifaceted bacterial infection with common features. It absolutely requires surgery for remission. The duration and form of concomitant administration of antibiotic agents for adult patients is still based on expert opinion.
Uckay, Ilker   +5 more
openaire   +5 more sources

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

open access: yesAdvanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu   +9 more
wiley   +1 more source

Antibiotic treatment of osteomyelitis [PDF]

open access: yes, 2015
Osteomyelitis is the infection of the bone and bone marrow caused by many types of different pathogens and the causative agents, most commonly streptococcus aureus, and the cause of the infection is most often – prosthetics and wound infection.the thesis
Oulianski, Maria
core  

Chronic non-bacterial osteomyelitis (CNO) and chronic recurrent multifocal osteomyelitis (CRMO) with a focus on pamidronate therapy [PDF]

open access: yes
Chronic recurrent multifocal osteomyelitis (CRMO), also called chronic nonbacterial osteomyelitis (CNO) or nonbacterial osteomyelitis (NBO), is a rare autoinflammatory bone disease of unknown etiology.
Katerina Bouchalova, Zuzana Pytelova
core   +1 more source

Osteomyelitis [PDF]

open access: yes, 2012
If you want to learn more about osteomyelitis you should not miss this book. The editors are professionals and scientists working in health sciences and the chapters have been prepared by experts in the field, covering subjects related with the ...

core   +3 more sources

Osteomyelitis in Deep Sternal Wound Infections: Revisited—A Single-Center Observational Study

open access: yesLife
Objective: Sternum osteomyelitis and deep sternal wound infection (DSWI) are often used to describe the same clinical condition interchangeably. The aim of our current study is to investigate the prevalence of osteomyelitis in cardiac surgery patients ...
Stephan Raab   +3 more
doaj   +1 more source

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