Results 101 to 110 of about 75,825 (256)

Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology

Clinical Endocrinology, EarlyView.
ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth, Thomas J. O'Leary, Craig L. Doig, Natalie Taylor, Jasminder Dosanjh, David R. Woods, Michael J. Stacey, Robert M. Gifford   +7 more
wiley   +1 more source

Impact of osteopenia and osteosarcopenia on the outcomes after surgery of hepatobiliary-pancreatic cancers

Frontiers in Oncology
ObjectiveThe purpose of this study is to investigate potential associations between osteopenia, osteosarcopenia, and postoperative outcomes in patients with hepatobiliary-pancreatic cancer (HBPC).MethodsThree online databases, including Embase, PubMed ...
Xiaofeng Wang, Min Wu, Qian Liu, Wei He, Yong Tian, Yan Zhang, Cuiping Li, Yanni Liu, Anqi Yu, Hongyan Jin   +9 more
doaj   +1 more source

Association of Cumulative Lead Exposure with Parkinson's Disease [PDF]

, 2010
BACKGROUND. Research using reconstructed exposure histories has suggested an association between heavy metal exposures, including lead, and Parkinson's disease (PD), but the only study that used bone lead, a biomarker of cumulative lead exposure, found a
Hersh, Bonnie, Hu, Howard, Nie, Huiling, Saint-Hilaire, Marie-Helene, Schwartz, Joel, Simon, David K., Sudarsky, Lewis, Weisskopf, Marc G., Weuve, Jennifer, Wright, Robert O.   +9 more
core   +3 more sources

Expanding Phenotype of GINS1 Deficiency: A Case Report and Review of the Literature

Clinical Genetics, EarlyView.
The authors present a novel case and review of individuals with GINS1 deficiency, causing severe growth restriction and combined immunodeficiency. Only the ninth case of this ultrarare disorder, it highlights the role of these variants in disease, glaucoma as a feature, and the possibility of immunodeficiency without infections in affected individuals.
Michael P. Mackley, Rae Brager, Hannah Geddie, Vicky Breakey, Rebecca Hough, Dimitrios J. Stavropoulos, Vanda McNiven   +6 more
wiley   +1 more source

Association between thyroid function and osteopenia or osteoporosis: a cross-sectional study in China

Scientific Reports
Thyroid dysfunction is associated with bone health, but the relationship with osteopenia remains unclear. This study aimed to investigate the association between thyroid function and osteopenia/osteoporosis across different age groups. The study included
Ling Zhang, Chao Ma, Xin Yin, Fenglian Zhang, Xiuyan Fang, Chen Zhang, Lei Shang, Li Ma   +7 more
doaj   +1 more source

The association between the AST/ALT ratio and osteopenia or osteoporosis in patients with type 2 diabetes mellitus

Endocrine Connections
Introduction: The aim of this study was to investigate the relationship between the AST/ALT ratio and osteopenia or osteoporosis in patients with type 2 diabetes mellitus (T2DM).
Yuan Zhang, Guanhua Chen, Shanshan Lv, Weimin Wang, Yali Jing   +4 more
doaj   +1 more source

The Diagnostic Odyssey of a Biochemically Confirmed Case of ML II: The First Western Patient With LYSET Deficiency

Clinical Genetics, EarlyView.
We identify a female patient with a homozygous nonsense variant (p.Gln38Ter) in the LYSET gene. This is the first western report of a challenging case of an extensive diagnostic odyssey and demonstrates that the LYSET gene must be considered in the differential diagnosis when M6P‐labeled lysosomal enzymes are altered.
Fernanda Sperb‐Ludwig, Taciane Alegra, Leonardo Martinello da Rosa, Nataniel Floriano Ludwig, Renata Voltolini Velho, Ida Vanessa Doederlein Schwartz   +5 more
wiley   +1 more source

Effect of Early Radiographic Bone Loss Before Loading on Implant‐Related Outcomes: A Long‐Term Retrospective Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This retrospective study primarily evaluated whether early radiographic bone loss (ERBL) predicts progressive bone loss (PBL), and secondarily assessed its association with implant survival and peri‐implant diseases. Methods Adults with dental implants who were followed for at least 5 years were included.
Dominick Moser, Engin Ozgur, Jennifer Tjokro, Clemens Raabe, Vivianne Chappuis, Gustavo Avila‐Ortiz, Pablo Galindo‐Moreno, Miguel Padial‐Molina, Emilio Couso‐Queiruga   +8 more
wiley   +1 more source

The temporal response of bone to unloading [PDF]

Rats were suspended by their tails with the forelimbs bearing the weight load to simulate the weightlessness of space flight. Growth in bone mass ceased by 1 week in the hindlimbs and lumbar vertebrae in growing rats, while growth in the forelimbs and ...
Bikle, D. D., Globus, R. K., Morey-Holton, E.   +2 more
core   +1 more source

Descrição atualizada da paralisia cerebral

Developmental Medicine &Child Neurology, EarlyView.
Resumo A paralisia cerebral (PC) é um termo descritivo amplamente utilizado para um espectro de deficiências motoras causadas por lesão ou malformação cerebral não progressiva ocorrida durante as fases iniciais do desenvolvimento. Avanços recentes nas áreas da genética, de pesquisa em inflamação e em neurofisiologia têm refinado a compreensão ...
Bernard Dan, Peter Rosenbaum, Lucinda Carr, Martin Gough, John Coughlan, Nonyelum Nweke   +5 more
wiley   +1 more source