Results 41 to 50 of about 75,825 (256)

Validation of a novel scoring system for changes in skeletal manifestations of hypophosphatasia in newborns, infants, and children: The Radiographic Global Impression of Change scale [PDF]

, 2018
Hypophosphatasia (HPP) is the heritable metabolic disease characterized by impaired skeletal mineralization due to low activity of the tissue-nonspecific isoenzyme of alkaline phosphatase.
Fujita, Kenji P, McAlister, William H, Moseley, Scott, Thompson, David D, Whyte, Michael P   +4 more
core   +2 more sources

m.10010T>C Mitochondrial Disease: A Case Report With Hypoparathyroidism and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Mitochondria are essential intracellular organelles that play a critical role in cellular metabolism, including the regulation of intracellular calcium signaling. Advances in genomic sequencing have facilitated the identification of rare pathogenic mitochondrial DNA (mtDNA) genetic variants in patients with unexplained endocrine disorders.
Jacob Mohr, Anja Lisbeth Frederiksen, Morten Duno, Anne Pernille Hermann, Trine Maxel Juul, Simone Rask Nielsen   +5 more
wiley   +1 more source

The estimated prevalence of osteoporosis in Bahrain: a multi-centered-based study

BMC Musculoskeletal Disorders
Objectives the primary aim of this study was to examine the prevalence and risk factors of low bone mineral density in Bahrain. Methods this was a retrospective study, which targeted a cohort of 4822 Bahraini subjects (mean age 59.36 years: 93% females).
Adla Bakri Hassan, Yasin I. Tayem, Mir Sadat-Ali, Amer J. Almarabheh, Abdulhameed Alawadhi, Ahsan J. Butt, Haitham Jahrami, Jamal Saleh, Mai E. Matar, Mansoor Shaikh, Salman k. Hasan, Ali R. Karashi   +11 more
doaj   +1 more source

Fatores associados à osteopenia e osteoporose em mulheres submetidas à densitometria óssea

Revista Brasileira de Reumatologia, 2015
O objetivo deste estudo foi determinar a prevalência de osteopenia e osteoporose em uma população de mulheres que fizeram exames de densitometria em uma clínica especializada no sul do Brasil.
Ana Carolina Veiga Silva, Maria Inês da Rosa, Bruna Fernandes, Suéli Lumertz, Rafaela Maria Diniz, Maria Eduarda Fernandes dos Reis Damiani   +5 more
doaj   +1 more source

Managing menopausal symptoms and associated clinical issues in breast cancer survivors [PDF]

, 2017
Objective: Review evidence to guide management of menopausal signs and symptoms in women after breast cancer and make recommendations accordingly. Evidence: Randomized controlled clinical trials, observational studies, evidence-based guidelines, and
Davis, Susan R., Gompel, Anne, Lumsden, Mary Ann, Pinkerton, JoAnn V., Santen, Richard J., Stuenkel, Cynthia A.   +5 more
core   +1 more source

Genetic prediction of blood cell reactivity and its potential causal influence on bone continuity and density disorders

Animal Models and Experimental Medicine, EarlyView.
We applied Mendelian randomization to explore causal links between blood cell traits and skeletal disorders. Using genetic instruments from large‐scale summary statistics, we assessed effects on bone continuity, density, and structural integrity. Sensitivity and reverse analyses confirmed robust associations, highlighting potential shared biological ...
Zhiqin Deng, Zhe Zhao, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Zhengyang Lin, Zhenhan Deng, Wencui Li   +8 more
wiley   +1 more source

Is Cervical Disc Arthroplasty an Effective Treatment for Cervical Degenerative Disease With Osteopenia?

Global Spine Journal
Study Design Retrospective case-control study. Objectives To evaluate postoperative outcomes of single-level cervical disc arthroplasty (CDA) in patients with osteopenia and compare these results with a matched cohort of normal bone mineral density (BMD).
Junbo He MD, Hua Chen MD, Tingkui Wu MD, Xin Rong MD, Chen Ding MD, Beiyu Wang MD, PhD, Hao Liu MD, PhD   +6 more
doaj   +1 more source

Audiovestibular functioning of post-menopausal females with osteoporosis and osteopenia

Journal of Otology, 2021
Introduction: Osteoporosis and osteopenia are progressive disorders characterized by decreased bone mass, especially in postmenopausal women. These can be associated with body pain, fractures, hearing loss and balance disorders. The present study aims to
Manisha K. Juneja, Sanjay Munjal, Anuradha Sharma, Ashok K. Gupta, Sanjay Bhadada   +4 more
doaj   +1 more source

The effect of three years of TNF alpha blocking therapy on markers of bone turnover and their predictive value for treatment discontinuation in patients with ankylosing spondylitis: a prospective longitudinal observational cohort study [PDF]

, 2012
INTRODUCTION: The aim of this study was to investigate the effect of three years of tumor necrosis factor-alpha (TNF-alpha) blocking therapy on bone turnover as well as to analyze the predictive value of early changes in bone turnover markers (BTM) for ...
Arends, S., Bos, R., Brouwer, E., Groen, H., Houtman, P.M., Kallenberg, C.G., Leijsma, M.K., Spoorenberg, A., van der Veer, E.   +8 more
core   +4 more sources

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

Advanced NanoBiomed Research, EarlyView.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei, Yogambha Ramaswamy, Young Jung No   +2 more
wiley   +1 more source