Results 41 to 50 of about 39,566 (236)

Extracellular vesicles rejuvenate the microenvironmental modulating function of recipient tissue-specific mesenchymal stem cells in osteopenia treatment

Frontiers in Endocrinology, 2023
Systemic transplantation of mesenchymal stem cells (MSCs), such as bone marrow MSCs (BMMSCs) and stem cells from human exfoliated deciduous teeth (SHED), is considered a prominent treatment for osteopenia.
Soichiro Sonoda, Takayoshi Yamaza
doaj   +1 more source

Hormone therapy (HT) in women with premature ovarian insufficiency or early menopause: Time to think of a new paradigm for healthy aging. A joint FIGO and IMS position paper

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an increased risk of cardiovascular, skeletal, cognitive and ...
Chiara Benedetto, Suvarna S. Khadilkar, Rossella E. Nappi, Andrea R. Genazzani, Federica Frezet, Laura Cucinella, Hema Divakar, Panagiotis Anagnostis, Nick Panay   +8 more
wiley   +1 more source

Osteopenia in childhood and adolescence

Romanian Journal of Pediatrics, 2014
Osteopenia, term of child pathologies, is a decrease in bone mass relative to chronological age, being an intermediate state between normal bone mass and osteoporosis. It has multiples etiological factors, comprising a heterogenic group of diseases of the connective tissue with genetic determinism and osteopenia gained in various pathological ...
Georgiana Russu, Tania Rusu, Ileana Ioniuc, Stela Gotia   +3 more
openaire   +2 more sources

Characterization of gut microbiota in the Uyghur osteopenia population

Scientific Reports
The objectives of this study were to investigate the composition of gut microbiota and its relationship with bone loss in the Uyghur osteopenia population, identify potential disease-related taxa and collect information for the prevention and treatment ...
Kunchen Teng, Xin Li, Ting Huang, Shuang Zhang, Qiuxi Zhang, Namuna Rousitemu, Ting Lan, Youfeng Wen   +7 more
doaj   +1 more source

Hemp (Cannabis sativa L.) Seed Protein and Its Hydrolysate Promote Bone Formation via the SMAD‐Dependent BMP Pathway

iNew Medicine, EarlyView.
ABSTRACT Objective With the global increase in aging populations, the prevalence of osteoporosis is rising. Current preventive and therapeutic strategies remain limited. The present study aimed to investigate the effects of hemp seed protein (HSP) and its hydrolysis‐derived bioactive peptides (HPH) on osteogenic differentiation and to elucidate their ...
Yan Wang, Jiameng Jia, Yang Yu, Kaiyuan Zheng, Meng Deng, Wei Chen, Guoming Liu, Ping Yi, Dongning Ling, Jing Zhang, Linfeng Liu, Bing Yang, Qing Wu, Ping Wei, Chong Yin   +14 more
wiley   +1 more source

Femoral Skeletal Growth in Early Infancy Assessed by Radiofrequency Echographic Multi‐Spectrometry

Journal of Clinical Ultrasound, EarlyView.
Radiofrequency echographic multi‐spectrometry (REMS) acquisition of raw ultrasound radiofrequency signals from neonatal bone. Signals undergo preprocessing and frequency‐domain analysis to extract spectral features reflecting bone properties. A software‐guided procedure then identifies and selects standardized regions of interest (ROIs).
Serafina Perrone, Virginia Beretta, Laura Cannavò, Domenico Corica, Tommaso Aversa, Giorgia Pepe, Letteria Morabito, Maria Elisabeth Street, Malgorzata Wasniewska, Tullio Ghi, Andrea Dall'Asta   +10 more
wiley   +1 more source

Causal association analysis between blood metabolomes and osteopenia and therapeutic target prediction for mechanomedicine

Mechanobiology in Medicine
Blood metabolomes have been linked to osteoporosis, yet the precise causal relationship with osteopenia, its preventable early stage, remains unclear. This study aimed to uncover the genetic causality between blood metabolomes and osteopenia, pinpointing
Ruobing Liu, Yaru Huang, Maogang Jiang, Fei Xu, Qilin Pei, Jiajun Ma, Youru Li, Siqi Shen, Bo Zhang, Xiangyang Guo, Jing Cai, Wenwen Wang   +11 more
doaj   +1 more source

Slow‐Phase Nystagmus Velocity as a Risk Factor for Lateral Canal BPPV Recurrence

The Laryngoscope, EarlyView.
This study investigated slow‐phase nystagmus velocity (SPV) at initial diagnosis as an objective vestibular predictor for the recurrence of lateral semicircular canal benign paroxysmal positional vertigo (BPPV). Binomial logistic regression analysis demonstrated that an elevated initial SPV is a novel, independent risk factor for recurrence ...
Chung Yoh Kim, Woo Jin Kim
wiley   +1 more source

HIGH FREQUENCY OF OSTEOPENIA IN YOUNG ADULTS OF KARACHI

Pakistan Journal of Medicine and Dentistry
Background: Osteopenia or low bone density, generally considered the disease of the old, is now sneaking around the younger generation. The increase in frequency of low trauma fractures is raising an alarm.
Moazzam Ali Shahid, Asma Niaz Khan, Maheen Nisar, Mustafa Ali Shah, Preet Roshan, Saeeda Baig   +5 more
doaj   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source