Results 151 to 160 of about 99,821 (371)

Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver

Immunity, 2020
Anneleen Remmerie, L. Martens, Tinne Thoné, Angela Castoldi, R. Seurinck, Benjamin Pavie, J. Roels, Bavo Vanneste, Sofie De Prijck, Mathias Vanhockerhout, Mushida Binte Abdul Latib, L. Devisscher, A. Hoorens, J. Bonnardel, N. Vandamme, A. Kremer, P. Borghgraef, H. Van Vlierberghe, S. Lippens, E. Pearce, Y. Saeys, Charlotte L. Scott   +21 more
semanticscholar   +1 more source

Co‐Treatment With rhBMP‐2 and Rapamycin Modulates Osteogenesis–Adipogenesis Balance to Enhance Aged Bone Regeneration

Advanced Science, EarlyView.
This study demonstrates that the imbalance between osteogenic and adipogenic differentiation in senescent BMSCs, leading to excessive adipocyte accumulation, which subsequently impairs bone regeneration in aged mice. To address this pathological dysregulation, a novel energy‐supplying hydrogel system (PBR) has been developed to restore balanced ...
Zirui He, Xiaoqiao Bai, Fangru Xie, Xuan Wang, Fan Zhang, Yuanman Yu, Yuan Yuan, Changsheng Liu   +7 more
wiley   +1 more source

Osteopontin attenuates early brain injury through regulating autophagy‐apoptosis interaction after subarachnoid hemorrhage in rats

CNS Neuroscience & Therapeutics, 2019
To determine the effect of osteopontin (OPN) on autophagy and autophagy‐apoptosis interactions after SAH.
Chengmei Sun, Budbazar Enkhjargal, C. Reis, Keren Zhou, Zhiyi Xie, Ling-Yun Wu, Tongyu Zhang, Qiquan Zhu, Ji-Ping Tang, Xiaodan Jiang, John H. Zhang   +10 more
semanticscholar   +1 more source

Pearl‐Like Bioinspired Coating Enables Regulation of Mg Degradation for Osteoporotic Bone Repair

Advanced Science, EarlyView.
In this study, inspired by pearl architecture, we developed a layered Ca–P “brick” and Fn‐mimetic peptide “mortar” coating on Mg alloys. The Ca–P layer moderates corrosion and offers mineral cues, while the peptide enhances adhesion and regulates immune‐vascular responses.
Siming Zhang, Tao Zhang, Yuan Chen, Nikolaos Kourkoumelis, Mo Chen, Jiale Dong, Zhenyu Li, Yanling Zhou, Ning Li, Chen Zhu, Xifu Shang, Jiaxiang Bai, Xianzuo Zhang   +12 more
wiley   +1 more source

Osteopontin: Versatile modulator of liver diseases [PDF]

, 2013
Sumiko Nagoshi
openalex   +1 more source

A Universal Metal–Flavonoid Coating Strategy: Engineering Biomaterials for Diabetic Bone Regeneration

Advanced Science, EarlyView.
Construction of metal–flavonoid functionalized coatings on conventional bone repair materials. A one‐pot method is used to directly construct multifunctional metal–flavonoid coatings on the surface of traditional bone repair materials by selecting metal ions with osteogenic/angiogenic properties and flavonoids with reactive oxygen species scavenging ...
Chen Yang, Chenle Dong, Lefeng Su, Zhiqiang Liu, Lingyi Hu, Qishu Jin, Hao Chen, Chunlong Zhang, Yihao Wu, Jiang Chang, Zhaowenbin Zhang, Jiandong Yuan   +11 more
wiley   +1 more source

Diagnostic value of osteopontin in ovarian cancer: a meta-analysis and systematic review.

PLoS ONE, 2015
AimsOsteopontin (OPN) plays an important role in many physiological and pathological processes (wound healing, inflammation, immune response, and tumorigenesis).
Zhi-De Hu, Ting-Ting Wei, Min Yang, Ning Ma, Qing-Qin Tang, Bao-Dong Qin, Hai-Tao Fu, Ren-Qian Zhong   +7 more
doaj   +1 more source

Programmatic regulation of macrophage polarization by HAp@MXene nanocomposites to promote bone repair

BMEMat, EarlyView.
HAp@MXene nanocomposites could achieve the programmed regulation of macrophage polarization. They first induce M1 polarization through magnetoelectric induction to combat infection. Subsequently, controlled Ca2+ release drives M2 polarization to promote tissue regeneration. This dual mechanism accelerates bone defect repair and highlights the potential
Laisen Cui, Haina Huang, Yubo Zheng, Jiahao Zhang, Han Hai, Kai Bian, Zhichao Feng, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Shan Lu, Bojun Xie, Ke Gao, Benjie Wei, Ya Liu, Chunhui Sun, Hong Liu, Chao Liu   +16 more
wiley   +1 more source

The Effects of Smoking on the Calcification of the Aortic Valve [PDF]

, 2016
Calcific Aortic Valve Disease is responsible for approximately 28,000 deaths annually and the complete mechanism is not completely understood. The disease is known to be effected by an inflammatory response, osteogenic response and an oxidative stress ...
Pendergraft, Brittany
core   +2 more sources

Na⁺/H⁺exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase [PDF]

, 2018
Nabeel Abdulrahman, Béatrice Jaspard‐Vinassa, Larry Fliegel, Aayesha Jabeen, Sadaf Riaz, Alain‐Pierre Gadeau, Fatima Mraiche   +6 more
openalex   +1 more source