Results 131 to 140 of about 305,673 (272)

Population level data on aging in periodontal and peri‐implant health—Aging is not a contraindication for periodontal or peri‐implant therapy

Periodontology 2000, EarlyView.
Abstract Objectives Global population aging is leading to a greater retention of natural teeth into later life and an increasing prevalence of dental implant therapy. Although advanced age has traditionally been regarded as a risk factor for compromised outcomes, population level evidence remains lacking.
Dong Yang, Jia Chang, Siyu Huang, Yvonne L. Kapila   +3 more
wiley   +1 more source

Shared molecular framework and bidirectional effects of osteoporosis on periodontal disease and dental implant therapy in the elderly

Periodontology 2000, EarlyView.
Abstract Objectives This review synthesizes evidence regarding the prevalence, epidemiological associations, and mechanistic pathways between osteoporosis, periodontal disease, and dental implant therapy. Materials and Methods A literature review was conducted to identify studies focused on: osteoporosis, periodontal disease, and dental implants ...
Samin Sirous, Jaclyn C. Chalmers, Pin‐Ying Li, Yumna Subhani, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source

A Perspective of Soy Isoflavones on Analytical, Biological, and Chemical Attributes

Legume Science, Volume 8, Issue 3, September 2026.
ABSTRACT This review covers key aspects of soybean (Glycine max), with a particular focus on its isoflavone content and biological properties. Soybeans maintain their position as both a nutraceutical and a pharmaceutical crop, with a broad range of dietary items used worldwide, including soy milk, fermented soy products, and various dietary supplements.
Sristy Suman, Joydeep Chatterjee, Gaurav Joshi, Raj Kumar, Muhammad Wahajuddin   +4 more
wiley   +1 more source

Effectiveness of Whole‐Body Vibration Therapy on Handgrip Strength: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Musculoskeletal Care, Volume 24, Issue 3, September 2026.
ABSTRACT Introduction Although whole‐body vibration (WBV) therapy has already demonstrated efficacy in improving lower‐limb muscle strength, it is still unclear whether it has similar potential for improving handgrip strength. Objective To verify the efficacy of WBV on handgrip strength. Methods The search was conducted on September 5, 2025, in PubMed,
Julien Dines Labarrere, Raphael Gonçalves de Oliveira, André Luiz de Campos Pessoa, Danúbia Cunha Sá‐Caputo, Mario Bernardo‐Filho, Liszt Palmeira de Oliveira   +5 more
wiley   +1 more source

Resveratrol: Advance on the Most Recent Research From 2021 to 2025

Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
This review summarizes recent progress in resveratrol research (2021–2025), highlighting its natural sources, bioactivities, clinical evidence, and safety profiles. Resveratrol exerts multi‐target effects through the regulation of oxidative stress, inflammation, mitochondrial function, and gut microbiota.
Quanyong Wu, Boya Ouyang, Yi Yuan, Jesus Simal‐Gandara, Hui Cao   +4 more
wiley   +1 more source

Management of postmenopausal osteoporosis.

Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia, 2013
Osteoporosis (OP) is a systemic skeletal disease characterised by low bone mass and micro-architectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture. Common sites of osteoporotic fractures are in the spine (vertebral), hip (proximal femur) or wrist (distal forearm).
Yeap SS, Hew FL, Chan SP
openaire   +2 more sources

Mind the gap: Adherence to denosumab dosing and cessation guidelines in Australian residential aged care

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2819-2827, August 2026.
This original research used medication administration data to explore adherence to treatment guidelines for the most common osteoporosis medications in long‐term residential aged care (RAC) in Australia. The paper highlights gaps in adherence to treatment guidelines that must be addressed to improve outcomes of older adults living in RAC.
Marea O'Donnell, Johanna I. Westbrook, Bayzidur Rahman, Isabelle Meulenbroeks, Nasir Wabe, Ian D. Cameron, Mark Morgan, Magdalena Z. Raban   +7 more
wiley   +1 more source

Discontinuing Long‐Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 334-344, August 2026.
Discontinuation of denosumab (Dmab) may be necessary due to adverse events or an unfavorable long‐term risk–benefit profile. However, accumulating evidence demonstrates pronounced rebound phenomena after withdrawal, most notably a marked increase in multiple vertebral fractures, and, in some reports, elevated mortality.
Ko‐Hsiu Lu, Renn‐Chia Lin, Ing‐Lin Chang, Shau‐Huai Fu, Meng‐Ying Tsai, Shun‐Fa Yang   +5 more
wiley   +1 more source

Lack of Differences in the Pharmacokinetics of Therapeutic Monoclonal Antibodies Between Japanese and Non‐Japanese Individuals

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta, Ashish Sharma, Bernd Meibohm   +2 more
wiley   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source