Low‐magnitude high‐frequency vibration (LMHFV), with or without 17β‐oestradiol (E2), exacerbated papain‐induced bovine intervertebral disc degeneration, reducing cell viability, impairing matrix production, and increasing inflammation. E2 showed no protective effect against papain‐induced degeneration or LMHFV.
Jan Ulrich Jansen +9 more
wiley +1 more source
Romosozumab and Denosumab Combination Therapy After Denosumab in Postmenopausal Osteoporosis
Objective Transition from long‐term denosumab (Dmab) to parathyroid hormone‐analogs or romosozumab (Romo) might expose patients to the risk of the so‐called rebound phenomenon. Adding Romo to Dmab might represent an option in patients experiencing a fracture while on Dmab.
Giovanni Adami +10 more
wiley +1 more source
Natural compounds regulate gut microbiota by improving microbial balance and increasing probiotics, which boost short‐chain fatty acid production to alleviate insulin resistance and inflammation. Additionally, they stimulate appetite‐suppressing hormones through bile acid signaling, while inhibiting pathogenic bacteria to repair intestinal barrier ...
Hongchao Yuan +7 more
wiley +1 more source
Egg yolk hydrolysate shows moderate impact on osteoporosis in ovariectomized rats
Abstract BACKGROUND This study investigated the protective effect of egg yolk hydrolysate (FC) on osteoporosis in ovariectomized (OVX) rats, a well‐established model of postmenopausal bone loss. OVX rats were fed diets supplemented with 0.2% or 1% FC for 13 weeks.
Ilekuttige Priyan Shanura Fernando +4 more
wiley +1 more source
Pathophysiology and Molecular Signalling in Osteoporosis: Linking Risk Factors to Bone Loss
ABSTRACT Osteoporosis is a prevalent skeletal disorder characterised by progressive reduction in bone mass, microarchitectural deterioration, and increased fracture susceptibility. In India, approximately one‐third of the elderly population is affected by bone‐related disorders, and the global burden of osteoporosis continues to rise.
Pramoda G. +5 more
wiley +1 more source
This study investigates human cortical bone remodeling space morphology and its relationship with age and sex using micro‐CT imaging. Remodeling space morphology exhibits great inter‐ and intraindividual variation. Its dimensions decrease with increasing age, but do not differ between sexes.
Xuan Wei +2 more
wiley +1 more source
Dysregulation of myddosome complex genes its related to alendronate treatment failure in osteoporosis postmenopausal patients. [PDF]
Oliveira BMR +5 more
europepmc +1 more source
Knowledge and practices of postmenopausal women regarding vitamin D and osteoporosis. [PDF]
Bastos-Silva Y +4 more
europepmc +1 more source
Revisiting Intranasal Salmon Calcitonin: Historical Osteoporosis Evidence and a Potential Role in Acute Orthopaedic Pain Management. [PDF]
Ahmad A +5 more
europepmc +1 more source
Low forearm bone density as a clue to suspect primary hyperparathyroidism in postmenopausal women with osteoporosis: a retrospective study. [PDF]
Soyer AK +6 more
europepmc +1 more source

