Results 181 to 190 of about 313,394 (308)

Targeting Mitochondria in Aging‐Related Diseases: Therapeutic Potential and Obstacles

MedComm, Volume 7, Issue 6, June 2026.
This article systematically summarized the specific mechanism of aging‐related diseases caused by mitochondrial dysfunction, and summarized the broad‐spectrum treatment methods and disease targeted treatment strategies for mitochondria. At the same time, it also pointed out the dilemma faced by mitochondrial targeted treatment.
Zijie Xiang, Yu Chen, Xishui Liu, Haowen Lu, Yuqing Yang, Lei Xing, Yu Zhang, Chuandong Lang, Siming Zhang, Shixiang Zhao, Youzhi Hong, Jiaxiang Bai, Yusen Qiao   +12 more
wiley   +1 more source

Unveiling the Power of Deuterium in Drug Discovery: A Comprehensive Overview

MedComm, Volume 7, Issue 6, June 2026.
The role of deuterium replacement in drug discovery, its progress, opportunities, and challenges. ABSTRACT Deuterium, the heavy isotope of hydrogen, has unfolded as a cornerstone in modern drug discovery due to its potential to influence metabolic stability and pharmacokinetic behavior.
Mukta Lele, Ajit Manchare, Swapnali Parit, Amol D. Gholap, Krishna Jadhav, Navnath Hatvate, Keshav Raj Paudel, Satish Rojekar   +7 more
wiley   +1 more source

Dietary Index for Gut Microbiota and Osteoporosis Risk in Chinese Postmenopausal Women: A Case-Control Study. [PDF]

Int J Womens Health
Yin X, Guan Y, Huang W.
europepmc   +1 more source

The Comparison of Effects of Alendronate and Raloxifene Treatment in Postmenopausal Women with Osteoporosis - Original Investigation

, 2006
This study was performed to assess and compare the effects of raloxifene and alendronate for the treatment of postmenopausal osteoporosis. Thirty-two women with postmenopausal osteoporosis (raloxifene group:16 patients, alendronate group: 16 patients ...
Ayhan Erkek, Cavidan Ay, Ömer Faruk Şendur, Bengü Beydağ Odabaşı, Gülcan Gürer   +4 more
core  

Senescent BMSC‐Derived Thbs1 Drives Inflammaging and Impairs Bone Regeneration by Suppressing PINK1/Parkin‐Mediated Mitophagy in Macrophages

Aging Cell, Volume 25, Issue 6, June 2026.
Aging BMSC‐derived Thbs1 activates the macrophage TGF‐β/Smad3 pathway to transcriptionally repress Pink1, impairing mitophagy and causing mitochondrial ROS accumulation. This redox imbalance drives M1 polarization and IL‐6 secretion. IL‐6 feeds back to BMSCs via the JAK/STAT3 pathway to inhibit osteogenesis and upregulate Thbs1, establishing a self ...
Yifeng Xing, Jingjing Su, Yanjun Lin, Nengwen Huang, Sihui Zhang, Yuwei Zhou, Jie Lu, Weiping Chen, Kaixun He, Wenxiu Yuan, Yang Li, Geyuan Zheng, Pengyuan Hu, Dong Wu, Yanjing Ou, Jiang Chen   +15 more
wiley   +1 more source

Awareness, attitudes and practices for osteoporosis prevention among postmenopausal women: A mixed-method survey and DEXA correlation. [PDF]

Bioinformation
Walulkar SM.
europepmc   +1 more source

Exploring Perimenopausal and Menopausal Women's Oral Health Perceptions and Practices in Australia—A Qualitative Study

Gerodontology, Volume 43, Issue 2, Page 198-210, June 2026.
ABSTRACT Objective To explore the perceptions and practices of women in peri/menopause towards oral healthcare in Australia. Background Hormonal changes associated with peri/menopause create a period where women may be more prone to developing oral health problems, which can significantly impact their quality of life.
Namitha Thomas, Kath Peters, Kate O'Reilly, Mariana S. Sousa, Ajesh George   +4 more
wiley   +1 more source

The endocrine pathway during whole body vibration modulates the immune system and the osteogenesis in postmenopausal women with osteoporosis. [PDF]

Front Endocrinol (Lausanne)
Pyatin V, Maslova O.
europepmc   +1 more source

Enhancing Breast Cancer Survivorship Care: The Role of Nurses in Post‐Treatment Follow‐Up—A Scoping Review

Journal of Advanced Nursing, Volume 82, Issue 6, Page 5659-5674, June 2026.
ABSTRACT Aim To examine the role of nurses in providing post‐treatment follow‐up care to breast cancer survivors, and to assess the impact of this care on survivors' satisfaction. Methods Scoping review. Data Sources An electronic literature search from PubMed and CINAHL databases was conducted, covering the period from 2013 to November 2023.
Judith Gálvez‐Sánchez, Nelia Soto‐Ruiz, Paula Escalada‐Hernández, Ana Carolina Andrade Biaggi Leite, Cristina García‐Vivar   +4 more
wiley   +1 more source

Romosozumab increases bone mineral density in postmenopausal Chinese women with osteoporosis: A randomised phase three study. [PDF]

J Orthop Translat
Zhenlin Z, Qingyun X, Decai C, Aijun C, Yanan H, Mei Z, Xu C, Hua L, Youjia X, Qun C, Huilin Y, Xiaoyan X, Yujie L, Xuan D, Jun J, LingLing G, Theresa RJ, Lars B, Weibo X.   +18 more
europepmc   +1 more source