Results 81 to 90 of about 37,163 (201)

Unilateral Dual‐Plane Puncture Percutaneous Vertebroplasty Reduces Re‐Collapse in Osteoporotic Vertebral Compression Fractures by Advancing Cement Delivery

Orthopaedic Surgery, Volume 17, Issue 5, Page 1322-1331, May 2025.
Trajectory of the unilateral dual‐plane puncture. The sagittal CT scan after surgery clearly shows the puncture trajectory of the unilateral dual‐plane puncture. The bone cement simultaneously contacted both the upper and lower end plates. ABSTRACT Purpose Evaluate the efficacy of a novel unilateral dual‐plane puncture technique in improving bone ...
Huo‐Liang Zheng, Chang‐hai Liu, Lei‐Sheng Jiang, Xin‐Feng Zheng, Sheng‐Dan Jiang   +4 more
wiley   +1 more source

Postmenopausal Osteoporosis: From Mechanisms to Modern Therapies

Quality in Sport
Background. Osteoporosis is the most common metabolic bone disease and represents a serious public health problem, particularly among postmenopausal women. It is characterized by reduced bone mineral density and bone microarchitecture disorders, leading
Jakub Lambach, Kacper Kutnik, Weronika Woźnica, Julia Matuszewska, Michał Białogłowski, Alicja Maziarczyk, Anna Gęborys, Katarzyna Mazurek, Maja Wojcieszak, Dominika Miazga   +9 more
doaj   +1 more source

Low‐dose lithium supplementation promotes musculoskeletal and metabolic health in ovariectomized female mice

The Journal of Physiology, EarlyView.
Abstract figure legend Low‐dose lithium supplementation in ovariectomized mice enhances skeletal muscle contractility (isometric force and fatigue resistance), SERCA function and promotes favourable transcriptional reprogramming, while increasing bone density and modestly improving insulin sensitivity.
Bianca M. Marcella, Jessica L. Braun, Amélie A.T. Marais, Briana L. Hockey, Mia S. Geromella, Ryan W. Baranowski, Rene Vandenboom, Rebecca E.K. MacPherson, Val A. Fajardo   +8 more
wiley   +1 more source

New advances in the study of postmenopausal osteoporosis and arteriosclerosis: Exploration of metabolite changes and their mechanisms

Archives of Gerontology and Geriatrics Plus
Postmenopausal women face a significantly increased risk of osteoporosis and arteriosclerosis due to a marked decline in estrogen levels, making it an important issue in public health. In recent years, metabolomic studies have revealed dynamic changes in
Yang Lei, Li Misi, Chen Xiaoyun, An Yangxin, Hu Xueqin, Li Weijuan   +5 more
doaj   +1 more source

Presenilin L166P Mutation, a Model of Familial Alzheimer's Disease, Leads to Early Onset Bone Loss

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
Female‐specific bone loss in Alzheimer's disease mouse models: There is a significant alteration of bone phenotype during Alzheimer's disease. Using integrated imaging and biological assays, we observed changes in the bone microarchitecture, composition, and function in PSEN K1 and PSEN1/hAPP Tg+ mice, predominantly in the females. ABSTRACT Accelerated
Vidyani Suryadevara, Connor J. Krehbial, Anuradha K. Valiya, Melinda Vang, Julian Balanta‐Melo, Pierre P. Eleniste, Sumana Posritong, Jung Min Hong, Katie Chester, Gabriel M. Pagnotti, Teresita Bellido, Monte S. Willis, Angela Bruzzaniti   +12 more
wiley   +1 more source

Vildagliptin and Omarigliptin Differentially Bind to DPP‐4 Homodimers and Modulate Osteoclast‐Mediated Bone Resorption

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
Vildagliptin and omarigliptin, dipeptidyl peptidase‐4 (DPP‐4) inhibitors, have differential effects on bone cells. Although vildagliptin improved the bone microstructure of high‐fat diet‐fed rats, it was unable to downregulate osteoclastogenesis or the expression of key osteoclast transcripts.
Ratchaneevan Aeimlapa, Jiraporn Panmanee, Jarinthorn Teerapornpuntakit, Kannikar Wongdee, Jirawan Thongbunchoo, Nattapon Panupinthu, Saovaros Svasti, Nattayaporn Apaijai, Piangkwan Sa‐nguanmoo, Siriporn Chattipakorn, Nipon Chattipakorn, Narattaphol Charoenphandhu   +11 more
wiley   +1 more source

Blood‐Based Lead Biomarkers and Sarcopenia Indicators in Older Adults

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Chronic exposure to low levels of lead (Pb) remains a widespread public health issue, especially among older adults. While its neurotoxic and cardiovascular effects are well recognized, its potential role in accelerating age‐related musculoskeletal decline is less understood.
Aida Koni, Alvaro Santos‐Cuerva, Mercedes Sotos‐Prieto, Rosario Ortolá, Pablo Olmedo, Javier García‐Pérez, Rebeca Ramis, Adrián Carballo‐Casla, Fernando Gil, Javier González‐Palacios, Roberto Pastor‐Barriuso, Ana Navas‐Acién, Elena Plans‐Beriso, Pablo Fernández‐Navarro, Fernando Rodríguez‐Artalejo, Esther García‐Esquinas   +15 more
wiley   +1 more source

Oxidative Stress: Molecular Mechanisms, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Oxidative stress occurs when the reactive oxygen species (ROS) production overwhelms the ROS scavenging, which lead to genomic instability, epigenetic regulation, proteostasis imbalance, and lipid peroxidation, subsequently causing the occurrence and development of numerous diseases. ABSTRACT Although the physiological level of reactive oxygen species (
Yi Qin, Chen Qian, Wenhao Li, Qihan Wang, Qifeng Sheng, Zheqing Chen, Wei Zhang, Wenming Li, Gaoran Ge, Zhanjun Yan, Dechun Geng   +10 more
wiley   +1 more source

Prevalence and Risk Factors of Osteoporosis among Postmenopausal Women Visiting a District Hospital of Nepal: An Observational Study

Journal of Nepal Medical Association
Introduction: Osteoporosis and low bone mass affect millions of people worldwide, leading to severe consequences ranging from disability to mortality.
Dipendra Pandey, Samina Basnet, Smeena Pradhananga, Sarita Shrestha, Badri Rijal, Aman Neupane, Utsav Timilsina, Amit Upreti, Apil Upreti, Rabindra Baskota, Pawan Kumar Hamal   +10 more
doaj   +1 more source

Avascular Necrosis and Minimal Trauma Fractures in Telomere Biology Disorders

Clinical Genetics, Volume 109, Issue 2, Page 286-293, February 2026.
Avascular Necrosis (AVN) and Minimal Trauma Fractures (MTF) cause significant morbidity in people with Telomere Biology Disorders (TBDs). They occur more frequently in young patients and in those with autosomal recessive (AR) or X‐linked recessive (XLR) than in autosomal dominant (AD) genotypes.
Arman M. Niknafs, Neelam Giri, Marena R. Niewisch, Sharon A. Savage   +3 more
wiley   +1 more source