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Patients with osteoporosis face a higher risk of bone injury, mainly due to weakened osteogenic differentiation and bone formation, along with increased osteoclast differentiation and bone resorption activity, leading to bone homeostasis imbalance.
Xinhui Wu+13 more
wiley +1 more source
Knowledge-based best of breed approach for automated detection of clinical events based on German free text digital hospital discharge letters [PDF]
OBJECTIVES: The secondary use of medical data contained in electronic medical records, such as hospital discharge letters, is a valuable resource for the improvement of clinical care (e.g. in terms of medication safety) or for research purposes. However,
Demuth, Ilja+4 more
core +1 more source
Analysing Osteoporosis Detection: A Comparative Study of CNN and FNN [PDF]
Osteoporosis causes progressive loss of bone density and strength, causing a more elevated risk of fracture than in normal healthy bones. It is estimated that some 1 in 3 women and 1 in 5 men over the age of 50 will experience osteoporotic fractures, which poses osteoporosis as an important public health problem worldwide.
arxiv
Associations between sedentary time, physical activity and bone health among older people using compositional data analysis [PDF]
Introduction : Aging is associated with a progressive decrease in bone mass (BM), and being physical active is one of the main strategies to combat this continuous loss.
Alegre, Luis M.+7 more
core +3 more sources
The study identified the significant increase in both crude death rate (224.79%) and DALY rate (196.27%) among the Chinese population affected by falls due to low bone mineral density, from 1990 to 2019. China witnessed a greater surge in deaths and DALYs compared with the global and other SDI areas. Projections indicate the mortality burden associated
Ping Wang+6 more
wiley +1 more source
CNN-based Automatic Detection of Bone Conditions via Diagnostic CT Images for Osteoporosis Screening [PDF]
Purpose: The purpose is to design a novelty automatic diagnostic method for osteoporosis screening by using the potential capability of convolutional neural network (CNN) in feature representation and extraction, which can be incorporated into the procedure of routine CT diagnostic in physical examination thereby improving the osteoporosis diagnosis ...
arxiv
Osteoporosis Circumscripta and Leontiasis Ossea Faciei Associated with Paget's Disease [PDF]
A. Elkeles
openalex +1 more source
Osteoporosis Prediction from Hand X-ray Images Using Segmentation-for-Classification and Self-Supervised Learning [PDF]
Osteoporosis is a widespread and chronic metabolic bone disease that often remains undiagnosed and untreated due to limited access to bone mineral density (BMD) tests like Dual-energy X-ray absorptiometry (DXA). In response to this challenge, current advancements are pivoting towards detecting osteoporosis by examining alternative indicators from ...
arxiv
Romosozumab for the treatment of osteoporosis
Romosozumab, a specific inhibitor of sclerostin, is a unique approach to therapy for postmenopausal osteoporosis and related disorders. The elucidation of sclerostin deficiency as the molecular defect of syndromes of high bone mass with normal quality ...
Michael R. McClung
doaj