Results 171 to 180 of about 291,165 (296)

Genetic Determinants of Treatment‐Related Bone Toxicity in Pediatric Acute Lymphoblastic Leukemia

Clinical Pharmacology &Therapeutics, EarlyView.
Osteonecrosis and fractures are serious corticosteroid‐induced bone toxicities in children treated for acute lymphoblastic leukemia, yet their genetic determinants remain incompletely defined. In this study, we aimed to identify novel genetic contributors to bone toxicity and to evaluate the robustness of both newly identified and previously ...
Rachid Abaji, Vincent Gagné, Émilie Espagne, Nathalie Alos, Veronica Del Vecchio, Lamia Ait Said, Albert Shalmiev, Claire Fuchs, Caroline Laverdière, Jean‐Marie Leclerc, Stephen E. Sallan, Lewis B. Silverman, Daniel Sinnett, Thai Hoa Tran, Maja Krajinovic   +14 more
wiley   +1 more source

Development and experimental validation of an osteoporosis diagnosis model based on disulfidoptosis-related genes and immune infiltration analysis. [PDF]

Front Immunol
Yang P, Chen M, Zhang J, Liu Z.
europepmc   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Co-creation and interprofessional collaborative practice for the local management of osteoporosis: a qualitative study in primary healthcare. [PDF]

Fam Pract
Nilsson J, Salminen H, Toth-Pal E, Ranch Lundin H.   +3 more
europepmc   +1 more source

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

Ensemble learning uncovers novel metabolomic biomarkers for early osteoporosis prediction in Tibetan plateau populations. [PDF]

Metabol Open
Yang J, Zhou T, Zhang H, Zhang Q, Chen L, Xiao Q, Luo S, Labasangzhu, Dunyou, Danbalangjie, Hao W, Wei X.   +11 more
europepmc   +1 more source

Disordered Eating Behaviors Among U.S. Children With Neuropsychiatric Conditions: A Nationally Representative Study

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study documented associations between parent‐reported disordered eating behaviors and co‐occurring anxiety, depression, behavioral/conduct problems, and attention‐deficit/hyperactivity disorder (ADHD) among U.S. children. Method Data were obtained from the combined 2022–2023 National Survey of Children's Health.
Myriam Casseus
wiley   +1 more source

Clinical Associations of Osteoporosis in BCR::ABL1 Negative Myeloproliferative Neoplasms. [PDF]

Int J Endocrinol
Aydin MS, Dagdas S, Pepeler MS, Korkmaz G, Alper A, Açıkgöz E, Bektas TN, Pamukçuoğlu M, Ceran F, Ozet G.   +9 more
europepmc   +1 more source

Strategic Priorities for Advancing Eating Disorder Risk Reduction: A Narrative Review

International Journal of Eating Disorders, EarlyView.
ABSTRACT Despite decades of advances in treatment, eating disorders continue to impose substantial individual and societal burden, underscoring the need for earlier and more effective risk reduction. Prevention research has expanded considerably, producing a wide range of approaches that target modifiable risk factors, build individual coping skills ...
Hannah K. Jarman
wiley   +1 more source

Computed tomography-measured trabecular attenuation at first lumbar vertebra as a surrogate marker of bone mineral density and osteoporosis in patients undergoing hemodialysis. [PDF]

Ren Fail
Yajima T, Kurisawa A, Arao M.
europepmc   +1 more source