Results 201 to 210 of about 673,953 (357)

Novel Sulfonylhydrazones With Sulfonate Ester Framework: Promising Dual Inhibitors of AChE and hCAs

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects millions of individuals worldwide. Treatment strategies for AD vary depending on cognitive and behavioral symptoms, with cholinergic replacement therapy using acetylcholinesterase (AChE) inhibitors being one of the primary approaches.
Cansu Öztürk, Neslihan Balci, Osman Nuri Aslan, Erbay Kalay   +3 more
wiley   +1 more source

Synthesis, Characterization, Biological Properties, and Sensor Applications of Novel Thiosemicarbazone Derivatives

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT In this study, novel thiosemicarbazone derivative molecules (5a–j) were synthesized. The characterization of the synthesized molecules was carried out using 1H–, 13C–NMR, FT–IR, and Q–TOF spectroscopic techniques. Then, the inhibitory effect of these compounds was examined for human carbonic anhydrase I and II (hCA I, and II) and ...
Hayreddin Gezegen, Oguz Özbek, Meryem Topal, Hatice Şahin, Ümit M. Koçyiğit   +4 more
wiley   +1 more source

MicroRNA-874-3p is a Potential Contributor to Primary Hyperparathyroidism-Induced Osteoporosis. [PDF]

Clin Interv Aging
Cheng K, Bai R, Li M, Wei Y, Li Z, Zhao X, Cao R, Wang Z, Tan S, Zha Y, Jiang X, Lu S.   +11 more
europepmc   +1 more source

Original paper Osteoporosis in rheumatoid arthritis patients – a real problem or fiction? Evaluation of incidence of vertebral fractures in rheumatoid arthritis in women under 50 years old [PDF]

, 2007
Piotr Leszczyński, Paweł Hrycaj, S Mackiewicz   +2 more
openalex  

Neck‐vein thrombosis during spaceflight

British Journal of Clinical Pharmacology, EarlyView.
Spaceflight imposes unique environmental challenges, including weightlessness, increased radiation exposure and confinement, which can lead to unexpected health effects. One such example is neck‐vein thrombosis, a condition rarely seen on Earth without predisposing factors such as venous catheters or infections.
Ulrich Limper, Jens Jordan
wiley   +1 more source

Face2Bone explainable AI model predicts osteoporosis risk from facial images in proof of concept study. [PDF]

Sci Rep
Liang Q, Zhao J, Yang F, Chen X, Song Y, Shi Z, Pang Q.   +6 more
europepmc   +1 more source

Ketogenic Diet Might Regulate Autophagy of Bmscs Via Mtor Signaling Contributing to Osteoporosis in Mice

Qi Liu, Yang Zhou, Yongnong Ye, Li R, Xueli Fan, Hang Lin, Jin Zhao, Xiuhua Wu, Qingàn Zhu   +8 more
openalex   +1 more source

A systematic review of medication adherence and mortality in chronic disease: Implications for clinical guidelines and policy

British Journal of Clinical Pharmacology, EarlyView.
Objectives This systematic review aims to investigate whether good medication adherence in adults with chronic conditions is associated with a lower mortality risk compared to poor adherence within published literature, and the extent to which this relationship is represented within South African policy and legislation.
Jessica Hamuy Blanco, Dina C. Janse van Rensburg, Audrey Jansen van Rensburg, Corrie Uys, Natalie Schellack   +4 more
wiley   +1 more source

Knowledge, attitudes, and practices on osteoporosis prevention and treatment strategies in the MENA region: a systematic review protocol. [PDF]

BMJ Open
Makarem Y, Sleem B, Chakhtoura MT, El Zein O, El-Hajj Fuleihan G.   +4 more
europepmc   +1 more source

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source