Results 201 to 210 of about 473,790 (360)

Molecular mechanisms, physiological roles, and therapeutic implications of ion fluxes in bone cells: Emphasis on the cation‐Cl− cotransporters

open access: yesJournal of Cellular Physiology, Volume 237, Issue 12, Page 4356-4368, December 2022., 2022
Ion transport systems in the membranes of osteoblasts and osteoclasts play a key role in bone remodeling by coordinating the movement of Ca2+, PO42−, and H+ ions in and out of the osseous matrix. Based on the evidence available, the cation‐Cl− cotransporters could act as unexpectedly important players in this regard.
Alexandre P. Garneau   +9 more
wiley   +1 more source

Utilization and expenditure on medicines for the management of osteoporosis in Ireland: A repeated cross‐sectional study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Osteoporosis is a prevalent skeletal disease characterized by low bone mass and increased fracture risk. Management of osteoporosis typically involves antiresorptive and anabolic therapies, which are reimbursed in Ireland through various drug schemes.
Amelia Smith   +4 more
wiley   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

open access: yesBMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu   +7 more
wiley   +1 more source

Chronic steroid use: An overlooked impact on patients with inflammatory bowel disease

open access: yesJGH Open, Volume 6, Issue 12, Page 910-914, December 2022., 2022
Steroids have long been used in inducing remission of inflammatory bowel disease (IBD), but there is controversy about whether IBD patients should be on chronic steroids for maintenance therapy. In this retrospective study, we aim to identify the complications of chronic steroid use in patients with IBD.
Kristen L Farraj   +7 more
wiley   +1 more source

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

open access: yesBMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah   +9 more
wiley   +1 more source

Unsupervised Machine Learning for Osteoporosis Diagnosis Using Singh Index Clustering on Hip Radiographs [PDF]

open access: yesarXiv
Osteoporosis, a prevalent condition among the aging population worldwide, is characterized by diminished bone mass and altered bone structure, increasing susceptibility to fractures. It poses a significant and growing global public health challenge over the next decade.
arxiv  

Early Detection of Osteoporosis by Dual Energy X-ray Absorptiometry [PDF]

open access: green, 1969
Asadullah Makhdoom   +3 more
openalex   +1 more source

Three‐ to 4‐year follow‐up of the reverse palatal pedicle graft for maxillary palatal recessions

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background This study evaluates the long‐term stability and clinical outcomes of the reverse palatal pedicle graft (RPPG) technique in treating maxillary molar palatal recessions over a 3 to 4‐year follow‐up period. Methods Three patients with palatal recession defects on maxillary molars were treated using the RPPG technique.
Thomas T. Nguyen   +2 more
wiley   +1 more source

Promising Prodiginins Biological Activities

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto   +6 more
wiley   +1 more source

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