Results 201 to 210 of about 291,165 (296)

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

Retinal biological age correlates with bone mineral density and fracture risk score and predicts incident osteoporosis. [PDF]

PLOS Digit Health
Peng Q, Xue CC, Chua K, Li H, Nusinovici S, Soh ZD, Gupta P, Leem AY, Yu MCY, Sabanayagam C, Rim TH, Zhu Z, Lamoureux E, Cheng CY.   +13 more
europepmc   +1 more source

The plant microbiome: From ecological foundations to precision microbial engineering for sustainable agriculture

iMeta, EarlyView.
From ecological principles to precision engineering of plant microbiomes for sustainable agriculture. The plant holobiont integrates diverse microbial niches (including rhizosphere, endosphere, phyllosphere, seed, and aerial‐root mucilagesphere), host genetics (namely M genes), and host metabolites. Furthermore, molecular dialogues, including rhizobial
Mi Wei, Tengxiang Lian, Liying Chen, Lanxiang Wang, Junjie Ye, Xiaofang Yao, Shilong Duan, Ziyu Lu, Jinji Tu, Hongfu Li, Xin‐Yue Xu, Jie Zhou, Junliang He, Feiying Zhu, Paola Bonfante, Lam‐Son Phan Tran, Zhiqiang Pang, Xin Zhou, Zhihui Xu, Lin Zhang, Mengcen Wang, Xiaolin Wang, Chang‐Fu Tian, Yong‐Xin Liu, Kai Sun, Ertao Wang, Xianan Xie   +26 more
wiley   +1 more source

Molecular mechanisms of polysaccharide components of kidney-tonifying traditional Chinese medicine in regulating osteoporosis. [PDF]

Front Pharmacol
Zheng Z, Yang F, Ye X, Jin Y, Zhu H, Zhou X, Zhang W, Li W, Shen NN.   +8 more
europepmc   +1 more source

Bazi Bushen Capsule restores fertility by targeting mitochondrial health in aging endometrium

iMeta, EarlyView.
Bazi Bushen Capsule (BZBS) mitigates age‐related endometrial dysfunction by activating AMPK − SIRT3 signaling. Luteolin, a key bioactive component, restores mitochondrial homeostasis via PINK1/Parkin−mediated mitophagy and Drp1 inhibition, improving endometrial function and fertility potential.
Shangqi Li, Feng Deng, Hongjuan Niu, Meng Li, Zeyang Lin, Jiayi Ma, Yue Wang, Yueqi Leng, Yunlong Hou, Wenwen Cui, Yang Yu, Heng Pan, Ping Zhou, Rong Li   +13 more
wiley   +1 more source

Preliminary Evaluation of a Large Language Model-Powered Chatbot for Osteoporosis Self-Management Education: Formative Randomized Controlled Trial. [PDF]

JMIR Form Res
Huang J, Xin X, He C, Xiong H, Pang W, Pang S, Sun W, Ding X.   +7 more
europepmc   +1 more source

Hemp (Cannabis sativa L.) Seed Protein and Its Hydrolysate Promote Bone Formation via the SMAD‐Dependent BMP Pathway

iNew Medicine, EarlyView.
ABSTRACT Objective With the global increase in aging populations, the prevalence of osteoporosis is rising. Current preventive and therapeutic strategies remain limited. The present study aimed to investigate the effects of hemp seed protein (HSP) and its hydrolysis‐derived bioactive peptides (HPH) on osteogenic differentiation and to elucidate their ...
Yan Wang, Jiameng Jia, Yang Yu, Kaiyuan Zheng, Meng Deng, Wei Chen, Guoming Liu, Ping Yi, Dongning Ling, Jing Zhang, Linfeng Liu, Bing Yang, Qing Wu, Ping Wei, Chong Yin   +14 more
wiley   +1 more source

REMS versus DXA in older adults: diagnostic concordance for osteoporosis in a geriatric outpatient population. [PDF]

Arch Osteoporos
Ceolin C, Noale M, Simonato C, Villanova F, Sturani S, Bertocco A, Giannini S, Arcidiacono GP, Busetto L, Antonini A, Coin A, Sergi G, De Rui M, O. P. A. working group.   +13 more
europepmc   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Association of prognostic nutritional index with fecal incontinence and fecal incontinence severity index in individuals with osteoporosis: mediating roles of C-reactive protein and gamma-glutamyl transferase. [PDF]

Front Nutr
Li F, Chen J, Zhou L, Yang C, Zhu Z.
europepmc   +1 more source