Results 231 to 240 of about 673,953 (357)

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki   +6 more
wiley   +1 more source

Assessing Severity in Anorexia Nervosa Using Alternative Criteria to the DSM‐5 in a Cross‐Sectional Study

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study compared overvaluation of weight and shape (OWS), drive for thinness (DT), and their combination (OWS‐DT) as alternative severity classifications for anorexia nervosa (AN) to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM‐5) severity classification.
Esther Henriet   +5 more
wiley   +1 more source

Osteosarcopenia as a risk factor for fractures and mortality - 19-year follow-up of a population-based sample. [PDF]

open access: yesAging Clin Exp Res
Blomqvist M   +5 more
europepmc   +1 more source

Romosozumab Treatment in Postmenopausal Women with Osteoporosis.

open access: yesNew England Journal of Medicine, 2016
F. Cosman   +16 more
semanticscholar   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

Cholecystectomy and the risk of osteoporosis and fractures: a systematic review and meta-analysis. [PDF]

open access: yesTher Adv Musculoskelet Dis
Sun G   +6 more
europepmc   +1 more source

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