Results 281 to 290 of about 472,200 (335)

Positive Association Between the Cardiometabolic Index and the Risk of Male Biochemical Androgen Deficiency in Adults

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic disorders are associated with testosterone deficiency, and the cardiometabolic index (CMI) is a recently identified metabolic indicator. The relationship between male biochemical androgen deficiency (MBAD), a precursor to testosterone deficiency, and CMI remains unclear.
Shuai‐Shuai Mao   +2 more
wiley   +1 more source

Monotropein Induced Ferroptosis to Alleviate the Progression of Hepatocellular Carcinoma via Regulating Nrf2/HO‐1/GPX4 Axis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) exhibits a high global morbidity rate and ranks as the fourth leading cause of cancer‐related mortality worldwide. In response to the urgent need for effective HCC treatments, naturally occurring, botanical‐driven compounds have gained increasing attention.
Bing Shi   +3 more
wiley   +1 more source

Routine‐data‐compatible quality indicators for the ambulatory care of osteoarthritis of the knee and hip: A systematic review

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Germany has high rates of total joint arthroplasty for osteoarthritis of the knee and hip. Ambulatory health interventions can affect the progression of these conditions and the need for total joint arthroplasty. Quality indicators and guideline recommendations facilitate the transparent measurement and demonstration of care quality ...
Tobias Bock   +5 more
wiley   +1 more source

The projected economic burden and complications of revision hip and knee arthroplasties: Insights from national registry studies

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract The rising volume of primary hip and knee arthroplasties has led to a parallel increase in revision surgeries, creating significant clinical and economic challenges for healthcare systems worldwide. This study synthesizes national arthroplasty registry data to evaluate trends in revision aetiology, associated costs and regional disparities ...
Patrick Sadoghi   +5 more
wiley   +1 more source

Diabetes and total knee arthroplasty: A nationwide analysis of complications, hospitalization outcomes and revision burden

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Total knee arthroplasty (TKA) is a frequently performed surgical procedure aimed at reducing pain, improving mobility, and restoring function in patients with advanced knee osteoarthritis. As patients undergoing TKA age, the prevalence of comorbidities, particularly diabetes, continues to rise.
Yaara Berkovich   +6 more
wiley   +1 more source

Reduction of Rescue Treatment With Dupilumab for Chronic Rhinosinusitis With Nasal Polyps in Japan

open access: yesThe Laryngoscope, EarlyView.
This observational study examined the impact of add‐on dupilumab treatment on the use of rescue therapy in Japanese individuals with chronic rhinosinusitis with nasal polyps (CRSwNPs) using data from a large hospital‐based administrative claims database.
Mamoru Yoshikawa   +5 more
wiley   +1 more source

Effects of a high‐fat diet on gut microbiota and possible implications for bone health in male Wistar rats

open access: yesLipids, EarlyView.
Abstract Diet plays an important role in the composition of gut microbiota. Emerging research suggests that bone homeostasis can also be influenced by the gut microbiota. The aim of this study was to assess possible alterations in gut microbiota in an experimental obesity model induced by a high‐fat diet (HFD) and the possible effects on parameters of ...
Fernanda Guedes Rodrigues   +6 more
wiley   +1 more source

Prevalence and Clinical Characteristics of the LRRK2 p.L1795F Variant in Central Europeans with Early‐Onset and Familial Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Leucine‐rich repeat kinase 2 (LRRK2) p.L1795F variant was proposed as a genetic risk factor for Parkinson's disease (PD). However, its prevalence, phenotype, and origin remain unknown. Objective The aim was to evaluate the frequency and phenotype of p.L1795F in early‐onset PD (EOPD) and familial PD compared to healthy controls (HC ...
Miriam Ostrozovicova   +35 more
wiley   +1 more source

Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Symptoms in Parkinson's Disease: Results from a Phase II Randomized Control Trial (STRIPE)

open access: yesMovement Disorders, EarlyView.
Abstract Background Lower urinary tract symptoms (LUTS) are common Parkinson's disease (PD), causing great impact. Objective The goal was to undertake a phase II randomized control trial of transcutaneous tibial nerve stimulation (TTNS) delivered by Geko device for LUTS related to overactive bladder (OAB) in PD, an easy to use of the shelf solution ...
Matthew D. Smith   +6 more
wiley   +1 more source

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