Results 41 to 50 of about 49,795 (263)

Preventing Osteoporosis in Postmenopausal Women: Treatment Approaches for Family Practitioners

South African Family Practice, 2008
Osteoporosis is defined as a systemic skeletal disorder that reduces the strength of bone, resulting in an increased risk of fracture. Fractures occur, even if an individual is subjected to minimal trauma such as a fall from own body height.
Tobie de Villiers
doaj   +1 more source

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source

Frequency and localization of osteoporotic fractures depending on age, bone mineral density and trabecular bone score in postmenopausal women of Ukrainian cohort

Bolʹ, Sustavy, Pozvonočnik, 2018
Background. Low-trauma fractures are the important complications of systemic osteoporosis, which lead to reduced quality of life, increased morbidity, disability and mortality. Nowadays, bone mineral density (BMD) and trabecular bone score (TBS) measured
V. Povoroznyuk, N. Grygorieva, T. Orlyk
doaj   +1 more source

Radiology reporting of incidental osteoporotic vertebral fragility fractures present on CT studies: results of UK national re-audit [PDF]

, 2023
David Howlett, K. Drinkwater, N. Mahmood, Loay Salman, Jill Griffin, M K Javaid, Ganesh Retnasingam, Abdelaziz Marzoug, Rebecca Greenhalgh, Andy Barrett, A. Chandegra, Abdallah Dabbas, A. Dhillon, A. Elstob, Anu Kamalasanan, Ayesha Mirza, Abdallah Mohamed, Asha Neelakantan, A.J. Paddon, Amit M. Patel, Amruta Radhakrishnan, Akash Shah, A Shenton, Aija Teibe, Brahman Dharmarajah, Cass Chisholm, Carolyn L. Cummins, C. Dick, Corinna Hauff, Claire McKeown, Constantinos O’Mahony, Danielle Campbell, Dean Howarth, D. Kitsos, David Temperley, A. Hubraq, Ese Adiotomre, Emma Gerety, Elizabeth Jackson, Evangelos Skondras, Fay L. Barley, F. Chinwalla, F Haque, Frances M. K. Williams, Fiona Witham, Govind P. Agrawal, Gary M. Tse, G Tudor, H. Conley, H. Halbert, Harout Kolanjian, Hayley Moss, I. Anwar, Jehan Ghany, J. Green, Joshua M. Hare, Jeffrey T. Howard, J. Jalli, Jozef Lastik, J. Moloney, Jacob Taylor, Julie Walker, John J. Warner, J. Wylie, J-Y Chan, K Asante, Kassem Faraj, Kathryn Harrison, K. Hodnett, Kashif Hussain, K. Karamani, Keith W. Muir, Keval Patel, Kapil Shirodkar, Kul Ranjan Singh, Kelvin Tan, Kevin Taylor, L Boyce, Lekha Chandrasekharan, M. Abdallah, M. Alkhouly, M. Bodoceanu, M. Brochwicz‐Lewinski, Mary Ann Clark, M. Drumea, Maha Mahmoud Fahmy, Muhammad Masood Hassan, Kamal Jamil, M. Kay, Midhun Mohan, Mark Portet, Madeleine Sampson, Mehdi Siddiqui, M. Srivastava, Magdalena Szewczyk‐Bieda, Martin Tapp, Nameet Hattangadi, N. Lyle, Nicola J. Matcham, Oliver Cram   +99 more
openalex   +1 more source

Pearl‐Like Bioinspired Coating Enables Regulation of Mg Degradation for Osteoporotic Bone Repair

Advanced Science, EarlyView.
In this study, inspired by pearl architecture, we developed a layered Ca–P “brick” and Fn‐mimetic peptide “mortar” coating on Mg alloys. The Ca–P layer moderates corrosion and offers mineral cues, while the peptide enhances adhesion and regulates immune‐vascular responses.
Siming Zhang, Tao Zhang, Yuan Chen, Nikolaos Kourkoumelis, Mo Chen, Jiale Dong, Zhenyu Li, Yanling Zhou, Ning Li, Chen Zhu, Xifu Shang, Jiaxiang Bai, Xianzuo Zhang   +12 more
wiley   +1 more source

Occult Posterior Pelvic Ring Fractures in Elderly Patients with Osteoporotic Pubic Rami Fractures

Journal of Orthopaedic Surgery, 2010
Purpose. To evaluate postoperative walking status of elderly patients with osteoporotic pubic rami fractures with or without posterior pelvic ring fractures. Methods.
Tak-Wing Lau, Frankie Leung
doaj   +1 more source

Enhanced Risk Stratification for Short-Term Complications Following Vertebral Augmentation for Osteoporotic Vertebral Compression Fractures [PDF]

, 2023
John I. Shin, Andrew R. Leggett, Ari R. Berg, Colin B. Harris, Aziz M. Merchant, Michael J. Vives   +5 more
openalex   +1 more source

CGRP Enhances the Regeneration of Bone Defects by Regulating Bone Marrow Mesenchymal Stem Cells Through Promoting ANGPTL4 Secretion by Bone Blood Vessels

Advanced Science, EarlyView.
ABSTRACT Bone angiogenesis is important for bone formation and regeneration after bone injury. Endothelial‐derived angiogenic factors are key signal transducers in the bone microenvironment and maintain vascular–osteogenic coupling during bone regeneration.
Qiong Lu, Qiyue Zheng, Zhaokai Zhou, Yajun Chen, Yun Chen, Wenjie Chen, Jiaojiao Wang, Ren Guo, Ren Wu, Lina Chen   +9 more
wiley   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

Using vital statistics to estimate the population-level impact of osteoporotic fractures on mortality based on death certificates, with an application to France (2000-2004)

BMC Public Health, 2009
Background We developed a methodology using vital statistics to estimate the impact of osteoporotic fractures on the mortality of an entire population, and applied it to France for the period 2000-2004.
Jougla Eric, Ziadé Nelly, Coste Joël
doaj   +1 more source