Results 61 to 70 of about 49,795 (263)

Plant‐derived extracellular vesicle‐like particles as novel osteoanabolic agents: Activating bone morphogenetic protein 2/Smads signaling axis for bone regeneration in postmenopausal osteoporosis

Interdisciplinary Medicine, EarlyView.
Illustration depicting the isolation of Dipsaci Radix derived extracellular vesicle‐like particles and their function in alleviating osteoporosis. (A) Extraction and characterization detection process of extracellular vesicle‐like particles derived from Dipsaci Radix roots. (B) Cell experiments in vitro, Dipsaci Radix derived extracellular vesicle‐like
Qing Zhao, Yue Cao, Zhengting Wu, Yingqi Cao, Qi You, Yuanyuan Xia, Xuejun Tan, Dongxiao Li, Tianxin Qiu, Xiuping Cai, Zhaodi Guo, Lei Zheng, Kewei Zhao   +12 more
wiley   +1 more source

Prevalence rate of osteoporosis complications in Ulan-Ude residents

Acta Biomedica Scientifica, 2015
We studied the frequency of osteoporotic fractures of different localizations in patients of 40 years and older living in Ulan-Ude. It was revealed that women have osteoporotic fractures 2,4 times more often than men.
T. I. Batudaeva, T. Y. Spasova
doaj  

Valproic Acid Inhibits Ferroptosis and Improves Bone Integration in OVX Rats Through the AMPK/SIRT1 Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The prevalence of postmenopausal osteoporosis (PMOP) has been steadily increasing. Ferroptosis has been recognized as a critical factor influencing the bone‐forming ability of bone marrow mesenchymal stem cells (BMSCs). Valproic acid (VPA), an HDAC inhibitor, has been suggested to play a role in regulating osteoporosis development; however ...
Qing‐Song Gu, Yi‐Fan Gu, Jian‐Qiao Li, Yi‐Heng Li, Yu‐Hu Chen, Lin‐Hui Wang, Zi‐Ru Wang, Yi‐Cong Wang, Min Yang   +8 more
wiley   +1 more source

Genetically predicted KIR2DS4 mediate the association between gut microbe K10 and osteoporosis fractures: A mediation Mendelian randomization study

PM&R, EarlyView.
Abstract Background Osteoporosis fractures pose a significant public health concern, leading to substantial morbidity and mortality rates. The emerging evidence on the potential link between gut microbiota, proteins, and osteoporosis fractures suggests a complex relationship that warrants further investigation.
Qiong Wang, Qing Kuang, Cheng Chen, Binru Wang, Wei Xiang, Xinming Li, Jianjiao Mou   +6 more
wiley   +1 more source

Clinical practice guidelines for the diagnosis and treatment of osteoporosis secondary to ankylosing spondylitis

Rheumatology &Autoimmunity, EarlyView.
Ankylosing spondylitis (AS) is a chronic inflammatory disease that primarily affects the axial skeleton and is often associated with secondary osteoporosis. Currently, there are no established international consensus or guidelines for managing AS‐related osteoporosis (AS‐OP). This guideline was jointly developed by several Chinese academic institutions,
Yasong Li, Liang Wang, Hongzhi Wang, Han Wang, Huaxiang Wu, Qifeng Ying, Dongbao Zhao, Lan He, Xuewu Zhang, Jian Zhu, Sanzhong Xu, Yi Yuan, Dun Hong, Peijian Tong, Ping Huang, Zhenchun Zhang, Hongwei Du, Yizhong Li, Xiaochun Zhu, Lijuan Wang, Zhangxuan Shou, Hao Zhang, Feng Huang, Weidong Xu   +23 more
wiley   +1 more source

Stratum Corneum Ceramide Abnormalities in Atopic Dermatitis: Pathophysiology and Implications for Disease Management

The Journal of Dermatology, EarlyView.
ABSTRACT The stratum corneum, as the outermost layer of the skin, functions as a critical barrier that maintains cutaneous hydration and systemic homeostasis. Among its structural lipids, ceramides constitute the most abundant and diverse component. These molecules are essential for the formation of lamellar structures that secure barrier integrity ...
Takashi Sakai
wiley   +1 more source

Osteoporotic Fracture Guidelines and Medical Education Related to the Clinical Practices: A Nationwide Survey in China

Orthopaedic Surgery, 2019
Objectives To investigate the knowledge and practices of Chinese doctors in the management of osteoporotic fractures after the Chinese osteoporotic fracture guidelines update and aseries of medical education in 2017.
Jin Lu, Zhong Ren, Xun Liu, You‐jia Xu, Qiang Liu   +4 more
doaj   +1 more source

CLINICAL AND INSTRUMENTAL CHARACTERISTICS OF REPEATED OSTEOPOROTIC FRACTURES IN PATIENTS OF GOMEL REGION OF BELORUSSIA AND MODERN THERAPEUTIC STRATEGY

Остеопороз и остеопатии, 2014
Introduction. Experienced osteoporotic fractures are a significant predictor of repeated, more severe fractures, entailing reduced quality of life and its expectancy. Objectives.
G N Romanov, N F Chernova, T I Moskvicheva, E V Rudenko   +3 more
doaj   +1 more source

Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones

, 2021
Lena Batoon, Susan Millard, Liza J. Raggatt, Cheyenne J. Sandrock, Edmund Pickering, Kyle Williams, Lucas W.H. Sun, Andy Wu, Katharine M. Irvine, Peter Pivonka, Vaida Glatt, Martin Wullschleger, David Hume, Allison R. Pettit   +13 more
openalex   +2 more sources

Clinical Practice Patterns in Bone Health Assessment and Management in Endogenous Cushing's Syndrome

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Skeletal fragility is a common complication of endogenous Cushing's Syndrome (CS), although specific guidelines for managing bone health are lacking. This study aimed to assess clinicians' current engagement with bone health assessment and management in patients with endogenous CS. Design Retrospective‐cohort design. Patients Seventy‐
Preeshila Behary, Dinushan Raveendran, Ramesh Nair, Aimee Di Marco, Debbie Papadopoulou, Florian Wernig, Ali Abbara, Karim Meeran, Niamh Martin, Jeremy Cox, Alexander N. Comninos   +10 more
wiley   +1 more source