Results 51 to 60 of about 1,079,622 (218)

Musculoskeletal decay and bone–muscle crosstalk during physical disuse: Mechanisms and integrated countermeasures

Experimental Physiology, EarlyView.
Abstract Older adults experience a markedly increased risk of falls and fractures following hospital discharge, largely due to the rapid musculoskeletal deterioration associated with bed rest. Although age‐related muscle and bone loss typically develops gradually, acute physical inactivity accelerates key biological processes underlying sarcopenia and ...
Julia Margarita Reyes, Guy Hajj‐Boutros, Dounia Rouabhia, José Morais, Felipe Salech, Gustavo Duque   +5 more
wiley   +1 more source

Biomechanical, Structural, and Composition Characterization of the Vertebra‐Disc Interface

JOR SPINE, Volume 9, Issue 4, December 2026.
ABSTRACT Background The spinal endplate region consists of the cartilage endplate (CEP), bony endplate (BEP), and subchondral trabecular bone (STB). Although this region is often involved in vertebral fractures and disrupted with disc degeneration, the biomechanics of these tissues are incompletely understood. The goal of this study was to characterize
Neilesh R. Frings, Harrah R. Newman, Faysal M. Haque, Veronica A. Caruso, Dawn M. Elliott, Elise F. Morgan   +5 more
wiley   +1 more source

When, where and how osteoporosis-associated fractures occur: An analysis from the global longitudinal study of osteoporosis in women (GLOW) [PDF]

, 2013
Objective: To examine when, where and how fractures occur in postmenopausal women. Methods: We analyzed data from the Global Longitudinal Study of Osteoporosis in Women (GLOW), including women aged ≥55 years from the United States of America, Canada ...
Anderson, Frederick A, Adachi, JD, Stephen H Gehlbach, Universitat Autònoma de Barcelona. Departament de Medicina, Adachi, Jonathan D., Chapurlat, Roland D., Frederick H Hooven, Díez Pérez, Adolfo, Nelson B Watts, Adachi, Jonathan D, Nieves, JW, Netelenbos, J.C., Lyn March, Boonen, S, Saag, Kenneth G., Compston, Juliet E., Roux, Christian, Pfeilschifter, Johannes, Rossini, Maurizio, Boonen, Steven, Pfeilschifter J, Ethel S Siris, Boonen S, Siris, E.S., Anderson, F.A., LaCroix, Andrea Z., Siris, Ethel S., Adami, Silvano, Adami, S., Watts NB, Jeri W Nieves, Lacroix, A.Z., Watts, NB, Gehlbach SH, Roux, C., Maurizio Rossini, Compston, JE, Gehlbach, S.H., Costa AG, Pfeilschifter, J., Rossini, M., Christian Roux, Boonen, S., Greenspan SL, Susan L Greenspan, Watts, N.B., Compston JE, Costa, Aline G. [UNIFESP], Greenspan, Susan L., Gehlbach, SH, March, L., Adami, S, Saag KG, Roux, C, Adachi JD, Saag, KG, Anderson, Frederick A., Greenspan, SL, Compston, Juliet E, Anderson FA Jr, Saag, Kenneth G, Hooven, Frederick H., Netelenbos JC, Cooper, C., March, Lyn, Díez Pérez A, Nieves, Jeri W., Cooper, C, Adachi, J.D., March, L, Nieves, Jeri W, Hooven, F.H., Andrea Z LaCroix, Silverman S, LaCroix, Andrea Z, Kenneth G Saag, Watts, Nelson B, Adolfo Díez-Pérez, Chapurlat, RD, Saag, K.G., Aline G Costa, Silverman, Stuart, Rossini, M, Juliet E Compston, Compston, J.E., Diez-Perez, A., Diez-Perez, Adolfo, Wyman, Allison, Stuart Silverman, Chapurlat, Roland D, Anderson Jr, Frederick A., Nieves JW, Silverman, S., Netelenbos, J. Coen, Jonathan D Adachi, Roux C, Cyrus Cooper, Gehlbach, Stephen H., Siris, Ethel S, Netelenbos, J Coen, Roland D Chapurlat, Siris, ES, Frederick A Anderson, March L, Pfeilschifter, J, Costa, A.G., Hooven, FH, Allison Wyman, LaCroix, AZ, Gehlbach, Stephen H, Lacroix AZ, Chapurlat, Roland, Wyman, A., Chapurlat, R.D., Greenspan, Susan L, Díez-Pérez, A, Silvano Adami, Anderson, FA, Cooper, Cyrus, Costa, Aline G, Chapurlat RD, Wyman, A, J Coen Netelenbos, Hooven, Frederick H, Hooven FH, Siris ES, Steven Boonen, Wyman A, Silverman, S, Costa, Aline G., Greenspan, S.L., Watts, Nelson B., Johannes Pfeilschifter, Netelenbos, JC, Nieves, J.W., Costa, AG, Cooper C, Nieves Jeri W., Adami Silvano, Anderson Frederick A., Siris Ethel S., Cooper Cyrus, Adachi Jonathan D., Netelenbos J. Coen, Gehlbach Stephen H., Watts Nelson B., Díez-Pérez Adolfo, Silverman Stuart, Greenspan Susan L., Compston Juliet E., LaCroix Andrea Z., Saag Kenneth G., Rossini Maurizio, Wyman Allison, Boonen Steven, March Lyn, Hooven Frederick H., Pfeilschifter Johannes, Roux Christian, Chapurlat Roland D., Costa Aline G.   +160 more
core   +1 more source

The acute osteoporotic vertebral compression fracture. Its natural course and characteristics. [PDF]

, 2009
Aim: The overall aim of this thesis was to investigate the natural course and the characteristics of the acute osteoporotic vertebral compression fracture in order to better understand and improve treatment for this type of fracture.
Suzuki, Nobuyuki
core   +1 more source

Artificial intelligence in risk prediction and diagnosis of vertebral fractures

Scientific Reports
With the increasing prevalence of vertebral fractures, accurate diagnosis and prognostication are essential. This study assesses the effectiveness of AI in diagnosing and predicting vertebral fractures through a systematic review and meta-analysis.
Srikar R. Namireddy, Saran S. Gill, Amaan Peerbhai, Abith G. Kamath, Daniele S. C. Ramsay, Hariharan Subbiah Ponniah, Ahmed Salih, Dragan Jankovic, Darius Kalasauskas, Jonathan Neuhoff, Andreas Kramer, Salvatore Russo, Santhosh G. Thavarajasingam   +12 more
doaj   +1 more source

Major spinal surgery procedure on a high cardiovascular risk patient with symptomatic neural compression due to 1: Osteoporotic T12 compression fracture along with 2—L5/S1 spondylolisthesis

Journal of Spinal Surgery, 2014
Introduction: Osteoporotic vertebral fracture most common located at thoracolumbar junction, whereas most spondylolisthesis at L4-5 is six to 10 times more frequent involved than adjacent level.
Sumeet G Pawar, Premanand Ramani, I Sabri Ibrahim   +2 more
doaj   +1 more source

Characterizing bone metastases and skeletal‐related events in patients with well‐differentiated neuroendocrine neoplasms utilizing 68Gallium‐DOTATATE positron emission tomography

Journal of Neuroendocrinology, Volume 38, Issue 11, November 2026.
Abstract Tumors of neuroendocrine origin are a heterogenous group of related neoplasms which can arise from anywhere in the body. Neuroendocrine neoplasms (NENs) are categorized by site of origin, differentiation status and grade (Ki‐67 expression and/or mitotic rate), with significant prognostic variability accordingly. Historically, the prevalence of
Tucker W. Coston, Himil J. Mahadevia, Marie M. Plante, Alex Hochwald, Joseph M. Accurso, Akash Sharma, Geoffrey B. Johnson, Jonathan B. Ashman, A. Tuba Kendi, Mohamad Bassam Sonbol, Patrick W. McGarrah, Timothy J. Hobday, Thorvardur R. Halfdanarson, Jason S. Starr   +13 more
wiley   +1 more source

Risk Factors for New Vertebral Fracture After Percutaneous Vertebroplasty for Osteoporotic Vertebral Compression Fractures

, 2021
Zi-Long Zhang,1,2,* Jun-Song Yang,1,* Ding-Jun Hao,1 Tuan-Jiang Liu,1 Qi-Ming Jing2,* 1Department of Spine Surgery, Honghui Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China; 2Graduate School of Xi’an
Zhang ZL, Liu TJ, Jing QM, Yang JS, Hao DJ   +4 more
core  

Artificial Intelligence‐Driven Precision Bisphosphonate Therapy in Osteoporosis: Mechanisms, Clinical Applications, Risks, and Future Directions

Orthopaedic Surgery, Volume 18, Issue 11, Page 2309-2319, November 2026.
This comprehensive review integrates 17 benchmark studies to illustrate the transition of osteoporosis management toward precision medicine. The schematic highlights three key clinical applications: AI‐driven opportunistic screening from routine CTs, precision pharmacotherapy selection, and the predictive prevention of adverse events like MRONJ ...
Xiang Yao, Yicong Chao, Xiao Gu, Jingtao Peng, Jishan Yuan, Wei Shi, Fuguo Zhang, Qiwen Bao   +7 more
wiley   +1 more source

Dynamic Spine Hyperflexion Is Related to Vertebral Compression Fractures in Postmenopausal Women

Orthopaedic Surgery, 2023
Objective Previous studies on osteoporotic vertebral fractures are usually based on the neutral posture of spine; however, the fractures are usually associated with the flexion posture of spine.
Zhirong Zheng, Wenhao Hu, Tian Tian, Weibo Liu, Xiangyu Wang, Meng Gao, Yonggang You, Xuesong Zhang   +7 more
doaj   +1 more source