Cervical Spine Osteoradionecrosis [PDF]
, 2017 Osteoradionecrosis (ORN), a well-known complication of radiotherapy in the mandibular bone, is very rare in the cervical spine. The authors report the result of a 3-year follow-up of a 63-year-old female patient with ORN of the cervical spine.
Kimata, Yoshihiro +4 more
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Osteonecrosis of the jaws by intravenous bisphosphonates and osteoradionecrosis : a comparative study [PDF]
, 2009 Aims: We analyze the possible clinical differences between bone jaw exposed areas in ONJ (osteonecrosis of the jaws) and ORN (osteoradionecrosis). Patients and method: Group 1 was composed with 53 ONJ cases and group 2 with 20 ORN cases. In both groups
Bagán Sebastián, José Vicente +9 more
core +1 more source
Osteoradionecrosis in Subaxial Cervical Spine - a Rare and Devastating Complication: A Case Report [PDF]
Malaysian Orthopaedic Journal, 2017 Osteoradionecrosis, a rare complication of radiation therapy, is a slow progression disease which affects the surrounding structures of spinal components.
Rashid MZ +4 more
doaj +1 more source
Clinico-therapeutic management of osteoradionecrosis : a literature review and update [PDF]
, 2011 In the management of head and neck cancer, radiotherapy is usually a coadjuvant to surgery, or is applied on a palliative basis. The most important complication of such radiotherapy is osteoradionecrosis, which manifests as an area of exposed necrotic ...
Silvestre Donat, Francisco Javier +1 more
core +1 more source
The prevention and management of osteoradionecrosis of the jaw in patients with head and neck cancer: summary of the best evidence [PDF]
Yixue xinzhi zazhi, 2020 Objective Osteoradionecrosis is a serious complication of radiotherapy for head and neck cancer, which not only leads to severe decrease of life quality of head and neck cancer survivors but also increases the economic burden of patients.
Yu-Jie SHI +11 more
doaj +1 more source
Refining the definition of mandibular osteoradionecrosis in clinical trials: The cancer research UK HOPON trial (Hyperbaric Oxygen for the Prevention of Osteoradionecrosis) [PDF]
, 2017 Introduction:Mandibular osteoradionecrosis (ORN) is a common and serious complication of head andneck radiotherapy for which there is little reliable evidence for prevention or treatment.
Bickerstaff, Matt +4 more
core +1 more source
Journal of Translational Medicine, 2011 Background Bisphosphonate associated osteonecrosis of the jaw (BRONJ) implies an impairment in oral hard- and soft tissue repair. An understanding of the signal transduction alterations involved can inform therapeutic strategies.
Schlegel Karl A +7 more
doaj +1 more source
Frontiers in Oncology, 2023 BackgroundFLASH radiotherapy (RT) is a novel method for delivering ionizing radiation, which has been shown in preclinical studies to have a normal tissue sparing effect and to maintain anticancer efficacy as compared to conventional RT.
Betina Børresen +8 more
doaj +1 more source
The convergence of radiation and immunogenic cell death signaling pathways. [PDF]
, 2012 Ionizing radiation (IR) triggers programmed cell death in tumor cells through a variety of highly regulated processes. Radiation-induced tumor cell death has been studied extensively in vitro and is widely attributed to multiple distinct mechanisms ...
Barcellos-Hoff, Mary H +4 more
core +2 more sources
Osteoradionecrosis: Case report
Brazilian Dental Science, 2015 Patients undergoing radiotherapy alone or as part of the treatment of head and neck cancer are likely to develop osteoradionecrosis (ORN). Dental extractions have been inferred as the main triggering factor of ORN, particularly in mandibular molars.
Rosana Ferreira Silva +5 more
doaj +1 more source