Results 261 to 270 of about 213,774 (293)

Inhibition of Fibroblast Activation Protein‐α Ameliorates Intervertebral Disc Degeneration via Reduced Vascular Invasion in Cartilage Endplate

open access: yesCell Proliferation, EarlyView.
Schematic illustration showing that FAP‐α promoted angiogenesis, cytokine release and ECM degradation in the CEP degeneration of the intervertebral disc through upregulating the PI3K/Akt/HIF‐1α/VEGFA pathway. ABSTRACT Intervertebral disc degeneration (IDD) is a primary cause of low back pain, with the development of new blood vessels being a key ...
Hao‐Wei Xu   +4 more
wiley   +1 more source

Atypical Fibroxanthoma/Pleomorphic Dermal Sarcoma With Osseous Metaplasia: A Series of Three Cases

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) are rare mesenchymal tumors typically arising on sun‐damaged skin of the head and neck in elderly patients. PDS is a more aggressive tumor but with similar demographics, cellular morphology, immunohistochemical features, and genetic findings.
Taylor Novice   +3 more
wiley   +1 more source

Examining the Role of Artificial Intelligence in Assessment: A Comparative Study of ChatGPT and Educator‐Generated Multiple‐Choice Questions in a Dental Exam

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer   +4 more
wiley   +1 more source

Label‐free imaging of intracellular structures in living mammalian cells via external apodization phase‐contrast microscopy

open access: yesThe FEBS Journal, EarlyView.
External apodization phase‐contrast (ExAPC) microscopy enables label‐free visualization of diverse intracellular structures in living mammalian cells. By enhancing phase‐contrast imaging through optical apodization, ExAPC reveals fine subcellular details, such as lipid droplets and organelle contacts, without fluorescent labels.
Hiroshi Ohno   +19 more
wiley   +1 more source

Erratum: MicroRNA-300 Regulates the Ubiquitination of PTEN through the CRL4B<sup>DCAF13</sup> E3 Ligase in Osteosarcoma Cells. [PDF]

open access: yesMol Ther Nucleic Acids
Chen Z   +9 more
europepmc   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

open access: yesThe FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou   +4 more
wiley   +1 more source

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