Results 111 to 120 of about 38,581 (265)

Quizartinib Resistance Mutations and Treatment Outcomes in Relapsed or Refractory FLT3‐ITD–Positive AML

Cancer Science, EarlyView.
ABSTRACT Quizartinib is a FMS‐like tyrosine kinase 3 (FLT3) inhibitor indicated for FLT3 internal tandem duplication (FLT3‐ITD)–positive acute myeloid leukemia (AML). We aimed to evaluate quizartinib resistance mechanisms, in addition to efficacy and safety outcomes, in patients with relapsed or refractory FLT3‐ITD–positive AML.
Yuichiro Semba, Toshihiro Miyamoto, Senji Kasahara, Yoshikane Kikushige, Takahiro Maeda, Goichi Yoshimoto, Shuichi Ota, Akio Saito, Yuho Najima, Hiroki Hosoi, Daigo Niiya, Koji Kato, Koji Nagafuji, Takashi Akasaka, Tomohiko Kamimura, Atsushi Takita, Maiko Narahara, Tadashi Toki, Koichi Iwanaga, Koji Yonemoto, Mine Harada, Koichi Akashi   +21 more
wiley   +1 more source

Impact Absorption Power of Polyolefin Fused Filament Fabrication 3D‐Printed Sports Mouthguards: In Vitro Study

Dental Traumatology, Volume 41, Issue 2, Page 213-223, April 2025.
ABSTRACT Background/Aim This study aims to evaluate and compare the impact absorption capacities of thermoformed ethylene vinyl acetate (EVA) mouthguards and 3D‐printed polyolefin mouthguards used in sports dentistry applications. The objective is to determine whether 3D‐printed polyolefin mouthguards offer superior impact toughness compared to ...
Leonardo Mohamad Nassani, Samuel Storts, Irina Novopoltseva, Lauren Ann Place, Matthew Fogarty, Pete Schupska   +5 more
wiley   +1 more source

Mediating Effect of Protein Intake on the Association Between Number of Remaining Teeth and Functional Decline

Gerodontology, EarlyView.
ABSTRACT Objective To examine whether protein intake mediates the association between the number of remaining teeth and functional decline in older Japanese adults. Introduction Tooth loss has been associated with reduced protein intake and functional decline in older adults.
Urara Taguchi, Sachiko Ono, Minami Sugimoto, Jun Aida, Hiroyuki Hikichi, Satoshi Sasaki, Ichiro Kawachi, Kazuto Hoshi   +7 more
wiley   +1 more source

Unravelling the Role of Non-Clustered Polyketide Synthases and Key Metabolites in Ochratoxin a Accumulation by <i>Penicillium nordicum</i> in Salt-Rich Environments. [PDF]

Int J Mol Sci
Álvarez M, Gil-Serna J, Alba C, Roncero E, Patiño B.   +4 more
europepmc   +1 more source

Heritability of Productive, Reproductive and Carcass Traits in Pure‐Bred and Cross‐Bred Pigs: A Systematic Review and Meta‐Analysis

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Heritability (h2) is a key parameter in animal breeding, but its magnitude and consistency across pure‐bred (PB) and cross‐bred (CB) pig populations remain poorly understood. This study aimed to compare heritability estimates between PB and CB populations for economically relevant traits through a systematic review and meta‐analysis.
Wilber Hernández‐Montiel, Amada I. Osorio‐Terán, Víctor M. Meza‐Villalvazo, Adolfo Amador‐Mendoza, José Abad‐Zavaleta, Nicolás Valenzuela‐Jiménez, Mario Alberto Martínez‐Núñez   +6 more
wiley   +1 more source

Chronic exposure to aflatoxin B1, ochratoxin A, and citrinin in women and children and associated health risk characterization: blood biomonitoring evidence from rural Bangladesh. [PDF]

Environ Health
Kyei NNA, Cramer B, Humpf HU, Kuhn M, Sobhan S, Veerkamp J, Gabrysch S.   +6 more
europepmc   +1 more source

Linagliptin increases the expression of LRP2 independent of Nrf2 in streptozotocin‐induced diabetic mice

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Oxidative stress is thought to play a role in the onset and progression of diabetic nephropathy (DN). Nuclear factor erythroid‐related factor 2 (Nrf2) is a master regulator of antioxidant and detoxification pathways and provides cellular protection against oxidative stress.
Suratsawadee Promsuwan, Yumi Takiyama, Takao Takiyama, Yuri Takiyama, Hiroya Kitsunai, Hiroshi Nomoto   +5 more
wiley   +1 more source

Integrated computational analysis prioritizes candidate targets and pathways linking ochratoxin A exposure to hepatocellular carcinoma. [PDF]

PLoS One
Yang S, Liu H, Kou H, Lai L, Zhang X, Xu Y, Sun Y, Chen B.   +7 more
europepmc   +1 more source

Demise of the OTA.

Environmental Health Perspectives, 1996
openaire   +2 more sources

Human cerebral arterial morphogenesis explored by 3D microscopic imaging of cleared embryos: Bridging the gap between embryonic and adult anatomy

Journal of Anatomy, EarlyView.
We provide a description of human embryonic cerebral arterial development based on whole‐mount immunostaining, tissue clearing, three‐dimensional (3D) light‐sheet microscopy imaging, and anatomically informed virtual segmentation of human embryos. Findings are compared with adult radiological anatomy. We provide a detailed account of the development of
Eimad Shotar, Raphaël Blain, Aymeric Nadjem, Nermine Saidi, Megumi Inoue, Daniel Smith‐Paredes, Miccaella Vergara, Armelle Lesaunier, Quentin Rappeneau, Joséphine Blevinal, Gérard Couly, Julien Burel, Julien Allard, Kevin Premat, Stéphanie Lenck, Pierre‐Marie Chiaroni, Erwah Kalsoum, Maryne Toupin, Séverine Mazaud‐Guittot, Diane Rebourcet, Paolo Giacobini, Olivier Naggara, Hugo Gortais, Grégoire Boulouis, Alexis Guédon, Philippe Gailloud, Frédéric Glicenstein, Anaïs Favre, Frédéric Clarençon, Yorick Gitton, Alain Chédotal   +30 more
wiley   +1 more source