Results 111 to 120 of about 7,770,431 (303)

Prevalence of Chagas disease among Latin American immigrants in non-endemic countries: an updated systematic review and meta-analysisResearch in context

The Lancet Regional Health. Europe
Summary: Background: Chagas disease (CD), endemic in 21 Latin American countries, has gradually spread beyond its traditional borders due to migratory movements and emerging as a global health concern.
Gisele Nepomuceno de Andrade, Pau Bosch-Nicolau, Bruno R. Nascimento, Francisco Rogerlândio Martins-Melo, Pablo Perel, Yvonne Geissbühler, Caroline Demacq, Monica Quijano, Jonathan F. Mosser, Ewerton Cousin, Ísis Eloah Machado, Matheus Lucca A.C. Rodrigues, Antonio Luiz P. Ribeiro, Israel Molina   +13 more
doaj   +1 more source

"Francisco Goldman's The Ordinary Seaman: The Spectralization of the Other and the Zombie” [PDF]

, 2018
This volume is the product of a joint effort to bring together critical views "from the Old World" on the field of American Studies. The contributors are leading Americanists working in Spanish academia who believe in the importance of working on ...
Benito Sánchez, Jesús
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

How strong was the bottleneck associated to the peopling of the Americas? New insights from multilocus sequence data

Genetics and Molecular Biology
In spite of many genetic studies that contributed for a deep knowledge about the peopling of the Americas, no consensus has emerged about important parameters such as the effective size of the Native Americans founder population. Previous estimates based
Nelson J.R. Fagundes, Alice Tagliani-Ribeiro, Rohina Rubicz, Larissa Tarskaia, Michael H. Crawford, Francisco M. Salzano, Sandro L. Bonatto   +6 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

NERVOUS SOUNDS: AUDITIVE ASPECTS IN AMERICAN CITY TEXTS

Известия Южного федерального университета: Филологические науки, 2009
The article deals with sounds and noises as a new field of studies. It is my intention to establish a link between Modernism as a period defined by literary and cultural history on the one hand and soundscape studies on the other.
R. Gunzenhaeuser
doaj   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

SOME REFLECTIONS ON NEW YORK CITY\u27S DISABILITY LAW [PDF]

, 1989
The article provides a broad overview of general disability law, and the distinctive features of New York City\u27s disability law. The author introduces American human rights law as distinct in that it does not purport to advance the needs of the ...
Hammel, Robert
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source