Results 121 to 130 of about 7,737,788 (301)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Amerikan Akademisindeki Tasavvuf Araştırmalarında Köken ve Yabancı Etkisi Meselesi: Oryantalist Miras ve Güncel Yaklaşımlar/The Issue of Origin and Foreign Influence in Sufi Studies in the American Academy: Orientalist Legacy and Current Approaches

Oksident
From its inception, Orientalism employed the method of critical textual analysis , which later become foundational to Islamic studies, as they developed in parallel with biblical studies. As a natural consequence of vertical historiography, scholars have
Alirıza Farımaz
doaj   +1 more source

Time is Not a River\u27 The Implications of Mumbo Jumbo\u27s Pendulum Chronology for Coalition Politics [PDF]

, 2003
Ismael Reed\u27s 1972 novel, Mumbo Jumbo, proposes a unique chronological theory that requires a multiple-grounded understanding of time. An analysis of what could be called this pendulum chronology leads to a more complete understanding of the novel ...
Nimura, Tamiko Fiona
core   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

الفـــكـــــر التوسعـــــــي الأمريكــــــــي دراســــــة فلسفية فـي تأصـيـــل المفهــــوم Expansionary Thought Of U.S., philosophical Study at rooting concept

Journal Of Babylon Center For Humanities Studies, 2013
The importance of research in the fact that the subject in question had not been studies philosophical precedent, it is true that there are many who have discussed and written about (expansion and American imperialism), but they did not try to present ...
Essam Abdel-Hussein Naumann عصام عبد الحسين نومان
doaj  

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

[Review of] Frederick J. Dockstader. The Kachina and the White Man: The Influences of White Culture on the Hopi Kachina Cult [PDF]

, 1987
To the delight of scholars of Native American studies and all other readers with even a passing interest in traditional Puebloan cultures of the American Southwest, Frederick Dockstader\u27 s classic study, The Kachina and the White Man, now has been ...
Osborn, Nancy M.
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source