Results 71 to 80 of about 7,770,431 (303)

“Strangers to Themselves”

open access: yesAmericana
This small-scale study proceeds from Bruner (1987) and Fougère (2008) in using semi-structured interviews to elicit self-narratives from six American Studies majors at two universities in Hungary.
Thomas A. Williams
doaj   +1 more source

The Geopolitical Context of Chamorro Cultural Preservation in Guam, U.S.A. [PDF]

open access: yes, 2012
An unincorporated Pacific Island territory of the United States, Guam has been under American rule since 1 898. While proudly Chamorro, the descendants of indigenous islanders have been American citizens since 1 950. U.S.
Diaz, Maria-Elena D.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The New Crafts: On the Technization of the Workforce and the Occupationalization of Firms [PDF]

open access: yes, 1992
[Excerpt] In the late 1960s and early 1970s American students were told that the value of a college education was declining (see Freeman 1976). Although liberal arts students were particularly discouraged by reports of recent graduates driving taxicabs ...
Barley, Stephen R.
core   +1 more source

Exploring the Relationship between Business Elite Networks and Redistributive Social Policies in Latin American Countries [PDF]

open access: yes, 2019
Although the cohesion of business elites has been associated with income concentration and regressive policies, few studies have investigated in depth the role of business elite networks in macrosocial issues such as redistributive social policies.
Cárdenas, Julián
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Health Behaviors and Lifestyle Interventions in African American Breast Cancer Survivors: A Review

open access: yesFrontiers in Oncology, 2019
Background: African American breast cancer survivors have a higher incidence of estrogen receptor negative and basal-like (e.g., triple negative) tumors, placing them at greater risk for poorer survival when compared to women of other racial and ethnic ...
Raheem J. Paxton   +4 more
doaj   +1 more source

Borders Manifest: Racializing the Nicaraguan Refugee in Costa Rica [PDF]

open access: yes, 2019
I look to border responses of North American countries as refugees and migrants move across them to argue that border responses racialize the foreign other in receiving countries.
Twidwell, Theodore B.
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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