Results 91 to 100 of about 32,821,322 (259)
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Department of Animal & Poultry Sciences Newsletter, Spring 2009
Published twice a year, this newsletter details student, faculty, and staff accomplishments and activities in the Department of Animal and Poultry Sciences at Virginia ...
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Porcine deltacoronavirus (PDCoV) has been prevalent worldwide for over a decade, causing considerable economic damage to the pig industry and posing a potential threat to public biosecurity.
Kunli Zhang +12 more
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
The Department of Animal & Poultry Sciences Newsletter, Summer 2007
Published twice a year, this newsletter details student, faculty, and staff accomplishments and activities in the Department of Animal and Poultry Sciences at Virginia ...
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Department of Animal & Poultry Sciences Newsletter, Fall 2008
Published twice a year, this newsletter details student, faculty, and staff accomplishments and activities in the Department of Animal and Poultry Sciences at Virginia ...
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IntroductionPorcine Reproductive and Respiratory Syndrome (PRRS) is a highly contagious disease that causes reproductive disorders in sows and respiratory problems in pigs of different ages. It first appeared in the late 20th century in the United States
Zhaowen Ren +14 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Department of Animal & Poultry Sciences Newsletter, Fall 2006
Published twice a year, this newsletter details student, faculty, and staff accomplishments and activities in the Department of Animal and Poultry Sciences at Virginia ...
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