Results 211 to 220 of about 3,998,003 (341)

The age of authenticity anxiety: Artificial intelligence and emerging questions for mental health. [PDF]

PLOS Ment Health
Brown AD.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

The Prevalence of Computer Vision Syndrome Among Medical Students in Syria: A National Cross-Sectional Study. [PDF]

Health Sci Rep
Alhouri HN, Alhouri AN, Aldayeh L, Asaad SHA, Alashik Z, Torbey A, Zahrawi H, Arrouk DMN, Badran M, Shammout M, Abdalaal NZ, Koudsi A.   +11 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Virtual rescripting after loss using deepfake technology in prolonged grief treatment: a study protocol for a multiple baseline design. [PDF]

Eur J Psychotraumatol
Petkovski M, Knipschild R, Gevers T, Lenferink LIM.   +3 more
europepmc   +1 more source

An empirical analysis of journal policy effectiveness for computational reproducibility

Proceedings of the National Academy of Sciences of the United States of America, 2018
V. Stodden, Jennifer Seiler, Zhaokun Ma
semanticscholar   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Prevalence, Virulence Determinants, and Antimicrobial Resistance of <i>Staphylococcus aureus</i> and <i>Escherichia coli</i> Isolated from Computer Devices Used by Staff and Students at a Northern Thailand University. [PDF]

Pathogens
Upakut S, Siriphap A, Japa O, Watsing P, Bunpak P, Ta-In A, Inmanee C, Thepmalee C, Suwannasom N, Khoothiam K.   +9 more
europepmc   +1 more source

Use of Bioinformatics Tools in Different Spheres of Life Sciences

, 2014
Muhammad Aamer Mehmood, Ujala Sehar, N. Ahmad   +2 more
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source