Results 81 to 90 of about 9,021,901 (317)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Israel in Bureaus of Jewish Education [PDF]
, 1998 A report on the track record of bureaus in Israel education, and recommendations for partnerships with other community organizations to allow BJEs to be successful in intensifying, disseminating, and improving Israel education throughout North ...
Daniel J. Margolis, Shlomo Shimon
core
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Māori education and principles of self-determination in the twenty-first century. [PDF]
, 2001 This paper argues that self-determination to the greatest extent possible is a legitimate aspiration for Maori people. It is argued that in education this requires a philosophical and policy response more focused on Maori autonomy than can be provided ...
O’Sullivan, Dominic
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Sport and education: Sport in secondary schools for all or for some? [PDF]
, 2007 The place of sport in schools has always been controversial and struggled to gain legitimacy and acceptance as a part of the formal curriculum. While some commentators argue sport has no place in the curriculum, others claim it is too important to be ...
Grant, Bevan C., Pope, Clive C.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Health Professions Education, 2019 Purpose: Although they participate in interprofessional education and practice, little is known about stereotypes public health education students have of other health professions.
Sam White +8 more
doaj +1 more source
Democracy as Othering Within Finnish Education [PDF]
International Journal of Bias, Identity and Diversities in Education, 2018 The word democracy is frequently uttered by academics, politicians, and, generally within society. Phrases such as ‘democratic education', ‘democracy education' and ‘(student) participation' are often referred to within national curricula, policy briefings, and, teacher education/training and resources.
openaire +2 more sources