Results 171 to 180 of about 478,812 (267)

Multifunctional ligand engineering for pure-blue halide perovskite nanocrystal LEDs. [PDF]

Light Sci Appl
Swihart MT.
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Augmented reality in engineering education: Strategic design and evidence-based results. [PDF]

PLoS One
Donaire S, Barraza R, Martínez-Pagán P, Martínez-Segura MA, Álvarez L, Yepes-Bellver L, Yepes V.   +6 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Innovative Technologies for Articular Cartilage Repair: Research, Development, and Clinical Translation-A Narrative Review. [PDF]

J Funct Biomater
Lara-Bertrand AL, Lizarazo-Fonseca L, Correa-Araujo L, Salguero G, Silva-Cote I.   +4 more
europepmc   +1 more source

Why Women in Ireland Leave Science, Technology, Engineering and Math (STEM) for Careers in Other Disciplines and Factors Which Could Aid their Retention

The main objective of this study was to gain an in-depth understanding into why women leave STEM positions to pursue careers in other disciplines in Ireland. Sub-objectives were to consider the challenges women face in STEM and to discover the factors which could facilitate their retention in the future. The study considers the field of gender equality
openaire   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Engineering the nursing profession: China's academician system reform and its implications for interdisciplinary health workforce development. [PDF]

NPJ Digit Med
Zhou WQ, Zhang CR, Xing Y, Luan W.
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Editorial: Advancing animal reproduction: Artificial Intelligence, precision technologies and reproductive biotechnologies. [PDF]

Front Vet Sci
Pollard CL, Hashem NM, Sontakke SD, Comizzoli P.   +3 more
europepmc   +1 more source