Results 81 to 90 of about 478,812 (267)
QUANTITATIVE DEVELOPMENT OF ENGINEERING EDUCATION IN IRAN AND THE CHALLENGE OF IMPROVING ITS QUALITY
Today, higher education systems in general and engineering education in particular play a significant role in the sustainable development of countries. On the other hand, the production and development of different technologies has created new conditions
Reza Mohammadi +2 more
doaj +1 more source
A Engenharia pode ser definida como a aplicação do conhecimento científico, econômico, social e prático, com o objetivo de criar, inventar, desenhar, construir, manter e melhorar produtos e processos, por meio de recursos materiais e energias da natureza, contribuindo positivamente na resolução de projetos de interesse da sociedade.
Oliveira, Milena Borges de +4 more
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Manganese sand is a cost-effective and efficient material widely used in water treatment. This work presents a comprehensive bibliometric analysis of research trends on manganese sand from 1993 to 2024, based on data from the Web of Science Core ...
Bo Song +6 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
This paper provides a comprehensive review of the 75-year development of reactor engineering technology at the China Institute of Atomic Energy (CIAE).
ZHU Qingfu, LONG Bin
doaj +1 more source
Potential of Cognitive Computing and Cognitive Systems
Cognitive computing and cognitive technologies are game changers for future engineering systems, as well as for engineering practice and training. They are major drivers for knowledge automation work, and the creation of cognitive products with higher ...
Noor Ahmed K.
doaj +1 more source

