Results 121 to 130 of about 2,310,738 (305)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Disainisekkumiste integreeritud hindamine sinialadel tervise ja heaolu edendamiseks

A Thesis for applying for the degree of Doctor of Philosophy in Landscape Architecture.Väitekiri filosoofiadoktori kraadi taotlemiseks maastikuarhitektuuri erialal.ABSTRACT. This PhD, conducted under the BlueHealth project (Horizon 2020), enhanced public
Mishra, Himansu Sekhar
core   +1 more source

Special issue. Portals for life sciences: providing intuitive access to bioinformatic tools

, 2010
The topic ‘Portals for life sciences’ includes various research fields, on the one hand many different topics out of life sciences, e.g. mass spectrometry, on the other hand portal technologies and different aspects of computer science, such as usability
Kohlbacher, O., Peter Kacsuk, Gesing, S., van Hemert, J., Sandra Gesing, Kacsuk, P., Jano van Hemert, Oliver Kohlbacher   +7 more
core   +1 more source

On the Other Side of Science: the Coronavirus as a Social Fact and the Problem of Modernity. (The Impact of the Pandemic on Everyday Life)

In Medias Res, 2022
The significant impotence of science and the contradictions raised by the Corona-virus as current crisis, which unites and reveals inequalities, suggests a scrutiny of the idea of modernity, with relative considerations regarding the social sciences. In fact, the sociological points of approach to the epidemic are diverse.
openaire   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Determining The Health Literacy Levels of Students in The Faculty of Health Sciences and Comparing them with Students from Other Faculties

Sağlık ve Hemşirelik Yönetimi Dergisi
Aim: The aim of this study was to determine the health literacy levels of students enrolled in undergraduate programs and to investigate whether there is a difference in health literacy levels between students of the faculty of health sciences and ...
Metin Ateş, Salim Yılmaz, Koray Kopuz, Derya Karabay, Suat Peker   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Taimelehtede sisestruktuuri vanusest ja kasvamisaegsest temperatuurist tingitud muutused

A Thesis for applying for the degree of Doctor of Philosophy in Applied Biology.Väitekiri filosoofiadoktori kraadi taotlemiseks rakendusbioloogia erialal.ABSTRACT.
Kuusk, Vivian
core   +1 more source

Porphyrin-based electrospun nanomaterials for life science applications

BBA Advances
Porphyrins are renowned for their utility in photocatalysis, electronics, sensors, solar cell dyes, and environmental remediation. However, their potential in life sciences applications remains underexplored, particularly in the context of encapsulation ...
Ana C. Mendes, Nuno M.M. Moura, M. Amparo F․ Faustino, M. Graça P.M.S. Neves, Ioannis S. Chronakis   +4 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source