Results 101 to 110 of about 2,310,738 (305)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Agroforum Mare Balticum 2016 : conference proceedings : 19th - 21st April 2016, Tartu, Estonia

open access: yes, 2016
Conference proceedingsThe annual international agricultural forum Agroforum Mare Balticum will be held, already for the fourth time now, in Tartu, Estonia.
Estonian University of Life Sciences
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Nonlinear Dynamics, Psychology, and Life Sciences

open access: yes
Nonlinear Dynamics, Psychology, and Life Sciences publishes articles that augment the fundamental ways we understand, describe, model and predict nonlinear phenomena in psychology and the life and social sciences.
DIECI, ROBERTO
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

"In vitro 3-D total guidance and fitness" proceedings of the CellFit workshop 2018 and "Intercellular epigenomics" SEARMET and TRANSGENO joint workshop 2018 : Tartu, Estonia 10-11 April, 2018 [PDF]

open access: yes, 2018
About the European Co-operation in Science and Technology. The European Cooperation in Science and Technology (COST) is the oldest and widest European intergovernmental network for cooperation in research.
Estonian University of Life Sciences
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Noves col·leccions d'eBooks: Biomedical Sciences and Life Sciences i Springer Medicine. (Març 2018)

open access: yes, 2018
Imatge utilitzada per fer publicitat de novetats del CRAI de la Universitat de Barcelona - Vitrina Març 2018.El CRAI de la Universitat de Barcelona adquireix, aquest any 2018, les col·leccions d'eBooks de Springer Biomedical Sciences and Life Sciences i ...
Universitat de Barcelona. CRAI
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