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Strategies for the development of life sciences and technologies in Iran [PDF]

open access: yesمطالعات مدیریت راهبردی, 2021
Aim and introduction: The field of life sciences is one of the most important fields related to issues and issues affecting life, including pharmacy, therapeutic, and related technologies with direct and indirect effects on human health due to their ...
Mohammad Mahdi Ershadi   +2 more
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

University of Applied Sciences Wädenswil

open access: yesCHIMIA, 2002
The University of Applied Sciences Wädenswil offers three courses in Life Sciences and one course in Facility Management. The course in Food Technology is a three-year course.
Marco Bachmann
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Student teachers' views: what is an interesting life sciences curriculum?

open access: yesSouth African Journal of Education, 2011
In South Africa, the Grade 12 'classes of 2008 and 2009' were the first to write examinations under the revised Life Sciences (Biology) curriculum which focuses on outcomes-based education (OBE).
Rian de Villiers
doaj   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Thesaurus Ethics in the Life Sciences 3rd Edition

open access: yes, 2006
The project, which was initiated by the DRZE in 1999, brings together five partners who decided to pool their professional experience with various thesauri in order to create a new Thesaurus Ethics in the Life Sciences.

core  

SPORTS SCIENCES AND STRATEGIES OF IMPROVEMENT LIFE STYLES OF POPULATION [PDF]

open access: yesSport Mont, 2007
Sports sciences = physical activities. Quality of life = life style. Sports sciences can act as a factor within a life quality system, provided life style of the population can be improved by changed physical activities. Physical activity is related with
Nebojša Maksimović, Goran Vasić
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A novel avian intestinal epithelial cell line: its characterization and exploration as an in vitro infection culture model for Eimeria species

open access: yesParasites & Vectors
Background The gastrointestinal epithelium plays an important role in directing recognition by the immune system, and epithelial cells provide the host's front line of defense against microorganisms. However, it is difficult to cultivate avian intestinal
Huifang Chen   +10 more
doaj   +1 more source

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